Isolation of extracellular vesicles from small volume of sample by microfluidic aqueous two phase system

Bo Hoon Han, Seok Chung, Ji Yoon Kang

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Small volume handling of extracellular vesicle separation from plasma with high recovery efficiency is a major issue of point of care testing. This paper suggests a microfluidic aqueous two phase system for isolation of extracellular vesicles from small volume of body fluid samples. With our device, 83.43% of recovery efficiency with protein removal of 65.46% was achieved from less than 10 μL of sample. We expect that our device will provide more useful application in isolation of extracellular vesicles.

Original languageEnglish
Title of host publication22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018
PublisherChemical and Biological Microsystems Society
Pages2053-2055
Number of pages3
ISBN (Electronic)9781510897571
Publication statusPublished - 2018 Jan 1
Event22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018 - Kaohsiung, Taiwan, Province of China
Duration: 2018 Nov 112018 Nov 15

Publication series

Name22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018
Volume4

Conference

Conference22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018
CountryTaiwan, Province of China
CityKaohsiung
Period18/11/1118/11/15

Keywords

  • Extracellular vesicles
  • Human plasma
  • Microfluidic aqueous two phase system

ASJC Scopus subject areas

  • Chemistry(all)
  • Bioengineering
  • Chemical Engineering (miscellaneous)
  • Control and Systems Engineering

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