Joint labeling of multiple regions of interest (ROIS) by enhanced auto context models

Minjeong Kim, Guorong Wu, Yanrong Guo, Dinggang Shen

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)


Accurate segmentation of a set of regions of interest (ROIs) in the brain images is a key step in many neuroscience studies. Due to the complexity of image patterns, many learning-based segmentation methods have been proposed, including auto context model (ACM) that can capture highlevel contextual information for guiding segmentation. However, since current ACM can only handle one ROI at a time, neighboring ROIs have to be labeled separately with different ACMs that are trained independently without communicating each other. To address this, we enhance the current single-ROI learning ACM to multi-ROI learning ACM for joint labeling of multiple neighboring ROIs (called eACM). First, we extend current independently-trained single-ROI ACMs to a set of jointly-trained cross-ROI ACMs, by simultaneous training of ACMs for all spatially-connected ROIs to let them to share their respective intermediate outputs for coordinated labeling of each image point. Then, the context features in each ACM can capture the cross-ROI dependence information from the outputs of other ACMs that are designed for neighboring ROIs. Second, we upgrade the output labeling map of each ACM with the multi-scale representation, thus both local and global context information can be effectively used to increase the robustness in characterizing geometric relationship among neighboring ROIs. Third, we integrate ACM into a multi-atlases segmentation paradigm, for encompassing high variations among subjects. Experiments on Loni LPBA40 dataset show much better performance by our eACM, compared to the conventional ACM.

Original languageEnglish
Title of host publication2015 IEEE 12th International Symposium on Biomedical Imaging, ISBI 2015
PublisherIEEE Computer Society
Number of pages4
ISBN (Electronic)9781479923748
Publication statusPublished - 2015 Jul 21
Externally publishedYes
Event12th IEEE International Symposium on Biomedical Imaging, ISBI 2015 - Brooklyn, United States
Duration: 2015 Apr 162015 Apr 19

Publication series

NameProceedings - International Symposium on Biomedical Imaging
ISSN (Print)1945-7928
ISSN (Electronic)1945-8452


Other12th IEEE International Symposium on Biomedical Imaging, ISBI 2015
Country/TerritoryUnited States


  • Auto context model (ACM)
  • Labeling

ASJC Scopus subject areas

  • Biomedical Engineering
  • Radiology Nuclear Medicine and imaging


Dive into the research topics of 'Joint labeling of multiple regions of interest (ROIS) by enhanced auto context models'. Together they form a unique fingerprint.

Cite this