Kilovoltage radiotherapy for companion animals: Dosimetric comparison of 300 kV, 450 kV, and 6 MV X-ray beams

Jaehyeon Seo, Jaeman Son, Yeona Cho, Nohwon Park, Dong Wook Kim, Jinsung Kim, Myonggeun Yoon

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)

Abstract

Radiotherapy for the treatment of cancer in companion animals is currently administered by using megavoltage X-ray machines. Because these machines are expensive, most animal hospitals do not perform radiotherapy. This study evaluated the ability of relatively inexpensive kilovoltage X-ray machines to treat companion animals. A simulation study based on a commercial treatment-planning system was performed for tumors of the brain (non-infectious meningoencephalitis), nasal cavity (malignant nasal tumors), forefoot (malignant muscular tumors), and abdomen (malignant intestinal tumors). The results of kilovoltage (300 kV and 450 kV) and megavoltage (6 MV) X-ray beams were compared. Whereas the 300 kV and 6 MV X-ray beams provided optimal radiation dose homogeneity and conformity, respectively, for brain tumors, the 6 MV X-rays provided optimal homogeneity and radiation conformity for nasal cavity, forefoot, and abdominal tumors. Although megavoltage X-ray beams provided better radiation dose distribution in most treated animals, the differences between megavoltage and kilovoltage X-ray beams were relatively small. The similar therapeutic effects of the kilovoltage and 6 MV X-ray beams suggest that kilovoltage X-ray beams may be effective alternatives to megavoltage X-ray beams in treating cancers in companion animals.

Original languageEnglish
Pages (from-to)550-556
Number of pages7
JournalJournal of Veterinary Science
Volume19
Issue number4
DOIs
Publication statusPublished - 2018

Keywords

  • Companion animals
  • Radiation therapy
  • X-ray

ASJC Scopus subject areas

  • veterinary(all)

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