Label-free detection of zinc oxide nanowire using a graphene wrapping method

Juneseok You, Kuewhan Jang, Sangmyung Lee, Doyeon Bang, Seungjoo Haam, Chang Hwan Choi, Jinsung Park, Sung Soo Na

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Zinc oxide nanowires (ZnO NWs) have been attempted to various applications, such as piezoelectric devices, energy harvesting devices, self-powered nanosensors, and biomedical devices. However, recent reports have shown the toxic effect of ZnO NWs. In this report, we described the detection of ZnO NWs, for the first time using reduced graphene oxide (RGO) wrapping method. By wrapping RGO to ZnO NW (RGO-ZnO NW), we are able to aggregate ZnO NWs and increase the sensing performance. The detection measurement is based on the resonance frequency shift derived from mass variation of RGO-ZnO NW adsorption on the DNA immobilized resonator. The resonator is able to detect ZnO NWs with detection limit of 100ngmL-1 which is 2 order below the fatal toxic concentration of ZnO NWs in Human Monocyte Macrophages (HMMs). Furthermore, the resonator is able to detect ZnO NWs in real tap water, showing the potential as ZnO NWs screening platform in real environmental aqua system.

Original languageEnglish
Pages (from-to)481-486
Number of pages6
JournalBiosensors and Bioelectronics
Volume68
DOIs
Publication statusPublished - 2015 Jun 5

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Nanowires
Zinc Oxide
Graphite
Zinc oxide
Graphene
Labels
Oxides
Resonators
Poisons
Equipment and Supplies
Immobilized Nucleic Acids
Piezoelectric devices
Nanosensors
Energy harvesting
Macrophages
Adsorption
Limit of Detection
Monocytes
Screening
DNA

Keywords

  • Bioelectronics
  • Microelectromechanical systems
  • Nanowires
  • Sensors/biosensors
  • Zinc oxide

ASJC Scopus subject areas

  • Biophysics
  • Biomedical Engineering
  • Biotechnology
  • Electrochemistry

Cite this

Label-free detection of zinc oxide nanowire using a graphene wrapping method. / You, Juneseok; Jang, Kuewhan; Lee, Sangmyung; Bang, Doyeon; Haam, Seungjoo; Choi, Chang Hwan; Park, Jinsung; Na, Sung Soo.

In: Biosensors and Bioelectronics, Vol. 68, 05.06.2015, p. 481-486.

Research output: Contribution to journalArticle

You, Juneseok ; Jang, Kuewhan ; Lee, Sangmyung ; Bang, Doyeon ; Haam, Seungjoo ; Choi, Chang Hwan ; Park, Jinsung ; Na, Sung Soo. / Label-free detection of zinc oxide nanowire using a graphene wrapping method. In: Biosensors and Bioelectronics. 2015 ; Vol. 68. pp. 481-486.
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