Laparoscopic gastrojejunostomy versus duodenal stenting in unresectable gastric cancer with gastric outlet obstruction

Sa Hong Min, Sang Yong Son, Do Hyun Jung, Chang Min Lee, Sang Hoon Ahn, Do Joong Park, Hyung Ho Kim

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Purpose: To compare the outcome between laparoscopic gastrojejunostomy (LapGJ) and duodenal stenting (DS) in terms of oral intake, nutritional status, patency duration, effect on chemotherapy and survival. Methods: Medical records of 115 patients, who had LapGJ or duodenal stent placement between July 2005 and September 2015 in Seoul National University Bundang Hospital, have been reviewed retrospectively. Oral intake was measured with Gastric Outlet Obstruction Scoring System. Serum albumin and body weight was measured as indicators of nutritional status. The duration of patency was measured until the date of reintervention. Chemotherapy effect was calculated after the procedures. Survival period and oral intake was analyzed by propensity score matching age, sex, T-stage, comorbidities, and chemotherapy status. Results: Forty-three LapGJ patients and 58 DS patients were enrolled. Improvement in oral intake was shown in LapGJ group versus DS group (88% vs. 59%, P = 0.011). Serum albumin showed slight but significant increase after LapGJ (+0.75 mg/dL vs.-0.15 mg/dL, P = 0.002); however, there was no difference in their body weight (+5.1 kg vs.-1.0 kg, P = 0.670). Patients tolerated chemotherapy longer without dosage reduction after LapGJ (243 days vs. 74 days, P = 0.006) and maintained the entire chemotherapy regimen after the procedure longer in LapGJ group (247 days vs. 137 days, P = 0.042). LapGJ showed significantly longer survival than DS (220 vs. 114 days, P = 0.004). Conclusion: DS can provide faster symptom relief but LapGJ can provide improved oral intake, better compliance to chemotherapy, and longer survival. Therefore, LapGJ should be the first choice in gastric outlet obstruction patients for long-term and better quality of life.

Original languageEnglish
Pages (from-to)130-136
Number of pages7
JournalAnnals of Surgical Treatment and Research
Volume93
Issue number3
DOIs
Publication statusPublished - 2017 Sep 1
Externally publishedYes

Fingerprint

Gastric Outlet Obstruction
Gastric Bypass
Stomach Neoplasms
Drug Therapy
Survival
Nutritional Status
Serum Albumin
Body Weight
Propensity Score
Stents
Medical Records
Comorbidity
Quality of Life

Keywords

  • Gastric outlet obstruction
  • Gastrojejunostomy
  • Laparoscopy
  • Stents
  • Stomach neoplasms

ASJC Scopus subject areas

  • Surgery

Cite this

Laparoscopic gastrojejunostomy versus duodenal stenting in unresectable gastric cancer with gastric outlet obstruction. / Min, Sa Hong; Son, Sang Yong; Jung, Do Hyun; Lee, Chang Min; Ahn, Sang Hoon; Park, Do Joong; Kim, Hyung Ho.

In: Annals of Surgical Treatment and Research, Vol. 93, No. 3, 01.09.2017, p. 130-136.

Research output: Contribution to journalArticle

Min, Sa Hong ; Son, Sang Yong ; Jung, Do Hyun ; Lee, Chang Min ; Ahn, Sang Hoon ; Park, Do Joong ; Kim, Hyung Ho. / Laparoscopic gastrojejunostomy versus duodenal stenting in unresectable gastric cancer with gastric outlet obstruction. In: Annals of Surgical Treatment and Research. 2017 ; Vol. 93, No. 3. pp. 130-136.
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T1 - Laparoscopic gastrojejunostomy versus duodenal stenting in unresectable gastric cancer with gastric outlet obstruction

AU - Min, Sa Hong

AU - Son, Sang Yong

AU - Jung, Do Hyun

AU - Lee, Chang Min

AU - Ahn, Sang Hoon

AU - Park, Do Joong

AU - Kim, Hyung Ho

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AB - Purpose: To compare the outcome between laparoscopic gastrojejunostomy (LapGJ) and duodenal stenting (DS) in terms of oral intake, nutritional status, patency duration, effect on chemotherapy and survival. Methods: Medical records of 115 patients, who had LapGJ or duodenal stent placement between July 2005 and September 2015 in Seoul National University Bundang Hospital, have been reviewed retrospectively. Oral intake was measured with Gastric Outlet Obstruction Scoring System. Serum albumin and body weight was measured as indicators of nutritional status. The duration of patency was measured until the date of reintervention. Chemotherapy effect was calculated after the procedures. Survival period and oral intake was analyzed by propensity score matching age, sex, T-stage, comorbidities, and chemotherapy status. Results: Forty-three LapGJ patients and 58 DS patients were enrolled. Improvement in oral intake was shown in LapGJ group versus DS group (88% vs. 59%, P = 0.011). Serum albumin showed slight but significant increase after LapGJ (+0.75 mg/dL vs.-0.15 mg/dL, P = 0.002); however, there was no difference in their body weight (+5.1 kg vs.-1.0 kg, P = 0.670). Patients tolerated chemotherapy longer without dosage reduction after LapGJ (243 days vs. 74 days, P = 0.006) and maintained the entire chemotherapy regimen after the procedure longer in LapGJ group (247 days vs. 137 days, P = 0.042). LapGJ showed significantly longer survival than DS (220 vs. 114 days, P = 0.004). Conclusion: DS can provide faster symptom relief but LapGJ can provide improved oral intake, better compliance to chemotherapy, and longer survival. Therefore, LapGJ should be the first choice in gastric outlet obstruction patients for long-term and better quality of life.

KW - Gastric outlet obstruction

KW - Gastrojejunostomy

KW - Laparoscopy

KW - Stents

KW - Stomach neoplasms

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