Laparoscopic versus open gastrectomy for gastric cancer: Long-term oncologic results

Ju Hee Lee, Chang Min Lee, Sang Yong Son, Sang Hoon Ahn, Do Joong Park, Hyung Ho Kim

Research output: Contribution to journalArticle

28 Citations (Scopus)

Abstract

Background. Data are lacking regarding the oncologic safety of laparoscopic gastrectomy (LG) for the treatment of gastric cancer. The aim of this study was to compare the long-term outcomes of LG with open gastrectomy (OG) for the treatment of gastric cancer. Methods. A total of 1,874 patients underwent curative distal or total gastrectomy for gastric adenocarcinoma between May 2003 and December 2009 and were included in this retrospective study. Recurrence-free survival and recurrence pattern were compared according to each tumor stage, and a subgroup analysis was performed in advanced gastric cancer patients who underwent D2 lymphadenectomy. Results. Of 1,874 patients, 816 were treated with OG and 1,058 with LG. No differences were observed in recurrence-free survival rates between the LG and the OG groups for any tumor stage. The number of harvested lymph nodes was similar between the two groups when analyzed according to tumor progression, operative procedure, and extent of lymphadenectomy. There were no differences between the 2 groups when we compared recurrence patterns after stratifying for tumor stage. The subgroup analysis in advanced gastric cancer patients who underwent D2 lymphadenectomy showed that there was no difference in the recurrence-free survival rates for any tumor stage between the 2 groups. Multivariate analysis indicated that the type of operative approach did not influence recurrence in either early or advanced gastric cancer patients. Conclusion. LG for gastric cancer is an oncologically safe procedure with comparable long-term outcomes with OG.

Original languageEnglish
Pages (from-to)154-164
Number of pages11
JournalSurgery (United States)
Volume155
Issue number1
DOIs
Publication statusPublished - 2014 Jan 1
Externally publishedYes

Fingerprint

Gastrectomy
Stomach Neoplasms
Recurrence
Lymph Node Excision
Neoplasms
Survival Rate
Operative Surgical Procedures
Stomach
Adenocarcinoma
Multivariate Analysis
Retrospective Studies
Lymph Nodes
Safety
Survival
Therapeutics

ASJC Scopus subject areas

  • Surgery

Cite this

Laparoscopic versus open gastrectomy for gastric cancer : Long-term oncologic results. / Lee, Ju Hee; Lee, Chang Min; Son, Sang Yong; Ahn, Sang Hoon; Park, Do Joong; Kim, Hyung Ho.

In: Surgery (United States), Vol. 155, No. 1, 01.01.2014, p. 154-164.

Research output: Contribution to journalArticle

Lee, Ju Hee ; Lee, Chang Min ; Son, Sang Yong ; Ahn, Sang Hoon ; Park, Do Joong ; Kim, Hyung Ho. / Laparoscopic versus open gastrectomy for gastric cancer : Long-term oncologic results. In: Surgery (United States). 2014 ; Vol. 155, No. 1. pp. 154-164.
@article{4f32688ee5034438b19a4993880fabfa,
title = "Laparoscopic versus open gastrectomy for gastric cancer: Long-term oncologic results",
abstract = "Background. Data are lacking regarding the oncologic safety of laparoscopic gastrectomy (LG) for the treatment of gastric cancer. The aim of this study was to compare the long-term outcomes of LG with open gastrectomy (OG) for the treatment of gastric cancer. Methods. A total of 1,874 patients underwent curative distal or total gastrectomy for gastric adenocarcinoma between May 2003 and December 2009 and were included in this retrospective study. Recurrence-free survival and recurrence pattern were compared according to each tumor stage, and a subgroup analysis was performed in advanced gastric cancer patients who underwent D2 lymphadenectomy. Results. Of 1,874 patients, 816 were treated with OG and 1,058 with LG. No differences were observed in recurrence-free survival rates between the LG and the OG groups for any tumor stage. The number of harvested lymph nodes was similar between the two groups when analyzed according to tumor progression, operative procedure, and extent of lymphadenectomy. There were no differences between the 2 groups when we compared recurrence patterns after stratifying for tumor stage. The subgroup analysis in advanced gastric cancer patients who underwent D2 lymphadenectomy showed that there was no difference in the recurrence-free survival rates for any tumor stage between the 2 groups. Multivariate analysis indicated that the type of operative approach did not influence recurrence in either early or advanced gastric cancer patients. Conclusion. LG for gastric cancer is an oncologically safe procedure with comparable long-term outcomes with OG.",
author = "Lee, {Ju Hee} and Lee, {Chang Min} and Son, {Sang Yong} and Ahn, {Sang Hoon} and Park, {Do Joong} and Kim, {Hyung Ho}",
year = "2014",
month = "1",
day = "1",
doi = "10.1016/j.surg.2013.06.015",
language = "English",
volume = "155",
pages = "154--164",
journal = "Surgery",
issn = "0039-6060",
publisher = "Mosby Inc.",
number = "1",

}

TY - JOUR

T1 - Laparoscopic versus open gastrectomy for gastric cancer

T2 - Long-term oncologic results

AU - Lee, Ju Hee

AU - Lee, Chang Min

AU - Son, Sang Yong

AU - Ahn, Sang Hoon

AU - Park, Do Joong

AU - Kim, Hyung Ho

PY - 2014/1/1

Y1 - 2014/1/1

N2 - Background. Data are lacking regarding the oncologic safety of laparoscopic gastrectomy (LG) for the treatment of gastric cancer. The aim of this study was to compare the long-term outcomes of LG with open gastrectomy (OG) for the treatment of gastric cancer. Methods. A total of 1,874 patients underwent curative distal or total gastrectomy for gastric adenocarcinoma between May 2003 and December 2009 and were included in this retrospective study. Recurrence-free survival and recurrence pattern were compared according to each tumor stage, and a subgroup analysis was performed in advanced gastric cancer patients who underwent D2 lymphadenectomy. Results. Of 1,874 patients, 816 were treated with OG and 1,058 with LG. No differences were observed in recurrence-free survival rates between the LG and the OG groups for any tumor stage. The number of harvested lymph nodes was similar between the two groups when analyzed according to tumor progression, operative procedure, and extent of lymphadenectomy. There were no differences between the 2 groups when we compared recurrence patterns after stratifying for tumor stage. The subgroup analysis in advanced gastric cancer patients who underwent D2 lymphadenectomy showed that there was no difference in the recurrence-free survival rates for any tumor stage between the 2 groups. Multivariate analysis indicated that the type of operative approach did not influence recurrence in either early or advanced gastric cancer patients. Conclusion. LG for gastric cancer is an oncologically safe procedure with comparable long-term outcomes with OG.

AB - Background. Data are lacking regarding the oncologic safety of laparoscopic gastrectomy (LG) for the treatment of gastric cancer. The aim of this study was to compare the long-term outcomes of LG with open gastrectomy (OG) for the treatment of gastric cancer. Methods. A total of 1,874 patients underwent curative distal or total gastrectomy for gastric adenocarcinoma between May 2003 and December 2009 and were included in this retrospective study. Recurrence-free survival and recurrence pattern were compared according to each tumor stage, and a subgroup analysis was performed in advanced gastric cancer patients who underwent D2 lymphadenectomy. Results. Of 1,874 patients, 816 were treated with OG and 1,058 with LG. No differences were observed in recurrence-free survival rates between the LG and the OG groups for any tumor stage. The number of harvested lymph nodes was similar between the two groups when analyzed according to tumor progression, operative procedure, and extent of lymphadenectomy. There were no differences between the 2 groups when we compared recurrence patterns after stratifying for tumor stage. The subgroup analysis in advanced gastric cancer patients who underwent D2 lymphadenectomy showed that there was no difference in the recurrence-free survival rates for any tumor stage between the 2 groups. Multivariate analysis indicated that the type of operative approach did not influence recurrence in either early or advanced gastric cancer patients. Conclusion. LG for gastric cancer is an oncologically safe procedure with comparable long-term outcomes with OG.

UR - http://www.scopus.com/inward/record.url?scp=84899478025&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84899478025&partnerID=8YFLogxK

U2 - 10.1016/j.surg.2013.06.015

DO - 10.1016/j.surg.2013.06.015

M3 - Article

C2 - 24238126

AN - SCOPUS:84899478025

VL - 155

SP - 154

EP - 164

JO - Surgery

JF - Surgery

SN - 0039-6060

IS - 1

ER -