Large deformation diffeomorphic registration of diffusion-weighted images with explicit orientation optimization

Pei Zhang, Marc Niethammer, Dinggang Shen, Pew Thian Yap

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

We seek to compute a diffeomorphic map between a pair of diffusion-weighted images under large deformation. Unlike existing techniques, our method allows any diffusion model to be fitted after registration for subsequent multifaceted analysis. This is achieved by directly aligning the diffusion-weighted images using a large deformation diffeomorphic registration framework formulated from an optimal control perspective. Our algorithm seeks the optimal coordinate mapping by simultaneously considering structural alignment, local fiber reorientation, and deformation regularization. Our algorithm also incorporates a multi-kernel strategy to concurrently register anatomical structures of different scales. We demonstrate the efficacy of our approach using in vivo data and report on detailed qualitative and quantitative results in comparison with several different registration strategies.

Original languageEnglish
Title of host publicationLecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
Pages27-34
Number of pages8
Volume8150 LNCS
EditionPART 2
DOIs
Publication statusPublished - 2013 Oct 24
Externally publishedYes
Event16th International Conference on Medical Image Computing and Computer Assisted Intervention, MICCAI 2013 - Nagoya, Japan
Duration: 2013 Sep 222013 Sep 26

Publication series

NameLecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
NumberPART 2
Volume8150 LNCS
ISSN (Print)03029743
ISSN (Electronic)16113349

Other

Other16th International Conference on Medical Image Computing and Computer Assisted Intervention, MICCAI 2013
CountryJapan
CityNagoya
Period13/9/2213/9/26

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ASJC Scopus subject areas

  • Computer Science(all)
  • Theoretical Computer Science

Cite this

Zhang, P., Niethammer, M., Shen, D., & Yap, P. T. (2013). Large deformation diffeomorphic registration of diffusion-weighted images with explicit orientation optimization. In Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics) (PART 2 ed., Vol. 8150 LNCS, pp. 27-34). (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); Vol. 8150 LNCS, No. PART 2). https://doi.org/10.1007/978-3-642-40763-5_4