Large-scale, ultrapliable, and free-standing nanomembranes

Edward Kang, Jihee Ryoo, Gi Seok Jeong, Yoon Young Choi, Seung Min Jeong, Jongil Ju, Seok Chung, Shuichi Takayama, Sang Hoon Lee

Research output: Contribution to journalArticlepeer-review

46 Citations (Scopus)

Abstract

The creation and characterization of large-area ultrathin highly pliable free-standing PDMS membranes and their application to the study of cellular epithelia is described. The ultra-thin membranes permitted the straight forward calculation of cell monolayer moduli, derived from measured stress-strain curves. These measurements allowed the unprecedented detection of cellular-level injury in the epithelia caused by the rupture of cell-cell tight junctions in response to stretching.

Original languageEnglish
Pages (from-to)2167-2173
Number of pages7
JournalAdvanced Materials
Volume25
Issue number15
DOIs
Publication statusPublished - 2013 Apr 18

Keywords

  • epithelial monolayer's modulus
  • large-scale elastic nanomembrane
  • ultrathin PDMS membrane

ASJC Scopus subject areas

  • Materials Science(all)
  • Mechanics of Materials
  • Mechanical Engineering

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