Laser-ablative synthesis of aggregation-induced enhanced emission luminophore dyes in aqueous solutions

C. K. Lim, A. A. Popov, G. Tselikov, J. Heo, A. Pliss, Sehoon Kim, A. V. Kabashin, P. N. Prasad

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Methods of femtosecond laser ablation in deionized water were used to fabricate ultrasmall (< 2 nm), bare (ligand-free) organic luminophore DCEtDCS nanoparticles, which exhibit aggregation enhanced emission in the green range (533 nm) with the quantum yield exceeding 58% and provide no concentration quenching. In contrast to chemically synthesized counterparts, laser-synthesized DCEtDCS nanoparticles do not contain any organic impurities due to their preparation in aqueous medium and do not require surfactants to stabilize colloidal solutions, which makes them highly suitable for intracellular uptake and bioimaging. The highly negative surface charge of these nanoparticles impeded their cellular uptake, but when the surface was coated with chitosan, a cationic polymer, intracellular uptake in microglia was achieved. Using in vitro model, we finally demonstrate the efficient employment of ultrasmall and surfactant free fluorescent organic nanoparticles prepared by laser ablation as markers in bioimaging.

Original languageEnglish
Title of host publicationSynthesis and Photonics of Nanoscale Materials XVI
EditorsDavid B. Geohegan, Jan J. Dubowski, Andrei V. Kabashin
PublisherSPIE
ISBN (Electronic)9781510624566
DOIs
Publication statusPublished - 2019 Jan 1
Externally publishedYes
EventSynthesis and Photonics of Nanoscale Materials XVI 2019 - San Francisco, United States
Duration: 2019 Feb 22019 Feb 3

Publication series

NameProceedings of SPIE - The International Society for Optical Engineering
Volume10907
ISSN (Print)0277-786X
ISSN (Electronic)1996-756X

Conference

ConferenceSynthesis and Photonics of Nanoscale Materials XVI 2019
CountryUnited States
CitySan Francisco
Period19/2/219/2/3

Fingerprint

Dyes
Nanoparticles
Aggregation
Coloring Agents
Agglomeration
dyes
Synthesis
Laser
aqueous solutions
nanoparticles
Laser Ablation
Lasers
Surfactant
Laser ablation
synthesis
Surface-Active Agents
laser ablation
lasers
Surface active agents
surfactants

Keywords

  • aggregation-induced enhanced emission luminophore dyes
  • femtosecond laser ablation in water
  • fluorescent organic nanoparticles

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Computer Science Applications
  • Applied Mathematics
  • Electrical and Electronic Engineering

Cite this

Lim, C. K., Popov, A. A., Tselikov, G., Heo, J., Pliss, A., Kim, S., ... Prasad, P. N. (2019). Laser-ablative synthesis of aggregation-induced enhanced emission luminophore dyes in aqueous solutions. In D. B. Geohegan, J. J. Dubowski, & A. V. Kabashin (Eds.), Synthesis and Photonics of Nanoscale Materials XVI [109070U] (Proceedings of SPIE - The International Society for Optical Engineering; Vol. 10907). SPIE. https://doi.org/10.1117/12.2513821

Laser-ablative synthesis of aggregation-induced enhanced emission luminophore dyes in aqueous solutions. / Lim, C. K.; Popov, A. A.; Tselikov, G.; Heo, J.; Pliss, A.; Kim, Sehoon; Kabashin, A. V.; Prasad, P. N.

Synthesis and Photonics of Nanoscale Materials XVI. ed. / David B. Geohegan; Jan J. Dubowski; Andrei V. Kabashin. SPIE, 2019. 109070U (Proceedings of SPIE - The International Society for Optical Engineering; Vol. 10907).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Lim, CK, Popov, AA, Tselikov, G, Heo, J, Pliss, A, Kim, S, Kabashin, AV & Prasad, PN 2019, Laser-ablative synthesis of aggregation-induced enhanced emission luminophore dyes in aqueous solutions. in DB Geohegan, JJ Dubowski & AV Kabashin (eds), Synthesis and Photonics of Nanoscale Materials XVI., 109070U, Proceedings of SPIE - The International Society for Optical Engineering, vol. 10907, SPIE, Synthesis and Photonics of Nanoscale Materials XVI 2019, San Francisco, United States, 19/2/2. https://doi.org/10.1117/12.2513821
Lim CK, Popov AA, Tselikov G, Heo J, Pliss A, Kim S et al. Laser-ablative synthesis of aggregation-induced enhanced emission luminophore dyes in aqueous solutions. In Geohegan DB, Dubowski JJ, Kabashin AV, editors, Synthesis and Photonics of Nanoscale Materials XVI. SPIE. 2019. 109070U. (Proceedings of SPIE - The International Society for Optical Engineering). https://doi.org/10.1117/12.2513821
Lim, C. K. ; Popov, A. A. ; Tselikov, G. ; Heo, J. ; Pliss, A. ; Kim, Sehoon ; Kabashin, A. V. ; Prasad, P. N. / Laser-ablative synthesis of aggregation-induced enhanced emission luminophore dyes in aqueous solutions. Synthesis and Photonics of Nanoscale Materials XVI. editor / David B. Geohegan ; Jan J. Dubowski ; Andrei V. Kabashin. SPIE, 2019. (Proceedings of SPIE - The International Society for Optical Engineering).
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