Laser Microsurgery in Caenorhabditis elegans

Christopher Fang-Yen, Christopher V. Gabel, Aravinthan D.T. Samuel, Cornelia I. Bargmann, Leon Avery

Research output: Chapter in Book/Report/Conference proceedingChapter

64 Citations (Scopus)


Laser killing of cell nuclei has long been a powerful means of examining the roles of individual cells in C. elegans. Advances in genetics, laser technology, and imaging have further expanded the capabilities and usefulness of laser surgery. Here, we review the implementation and application of currently used methods for target edoptical disruption in C. elegans.

Original languageEnglish
Title of host publicationMethods in Cell Biology
PublisherAcademic Press Inc.
Number of pages30
Publication statusPublished - 2012

Publication series

NameMethods in Cell Biology
ISSN (Print)0091-679X


  • Ablation
  • Chemosensation
  • Laser killing
  • Microbeam
  • Microfluidics
  • Microsurgery

ASJC Scopus subject areas

  • Cell Biology

Cite this

Fang-Yen, C., Gabel, C. V., Samuel, A. D. T., Bargmann, C. I., & Avery, L. (2012). Laser Microsurgery in Caenorhabditis elegans. In Methods in Cell Biology (pp. 177-206). (Methods in Cell Biology; Vol. 107). Academic Press Inc..