Length of negative resection margin does not affect local recurrence and survival in the patients with gastric cancer

Chang Min Lee, Ye Seob Jee, Ju Hee Lee, Sang Yong Son, Sang Hoon Ahn, Do Joong Park, Hyung Ho Kim

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

AIM: To investigate the influence of the resection margin on local recurrence and survival in gastric cancer patients.

METHODS: We reviewed the medical records of 1788 patients who had undergone gastrectomy for gastric cancer at the Seoul National University Bundang Hospital, South Korea, between May 2003 and July 2009. The patients were divided into early and advanced gastric cancer groups. In each group, we analyzed the relationship between clinicopathologic factors and survival outcomes, and compared the hazard rates of event occurrence between patients with resection margins above and below the cut-off value, using a Cox proportional hazard model.

RESULTS: The early and advanced gastric cancer groups included 1001 and 787 patients, respectively. The hazard rates of event occurrence did not significantly differ between the patients with resection margins above the cut-off value and those with resection margins below the cut-off value (p < 0.05, in all comparisons). Based on the multivariable analyses, the proximal and distal resection margins were not significantly associated with survival outcomes and local recurrence (p < 0.05, in all analyses).

CONCLUSION: The proximal or distal resection margins did not affect the prognosis of patients with gastric cancer if the margins were pathologically negative.

Original languageEnglish
Pages (from-to)10518-10524
Number of pages7
JournalWorld Journal of Gastroenterology
Volume20
Issue number30
DOIs
Publication statusPublished - 2014 Aug 14
Externally publishedYes

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Stomach Neoplasms
Recurrence
Survival
Republic of Korea
Gastrectomy
Margins of Excision
Proportional Hazards Models
Medical Records

Keywords

  • Gastric cancer
  • Margin
  • Recurrence
  • Resection
  • Survival

ASJC Scopus subject areas

  • Gastroenterology

Cite this

Length of negative resection margin does not affect local recurrence and survival in the patients with gastric cancer. / Lee, Chang Min; Jee, Ye Seob; Lee, Ju Hee; Son, Sang Yong; Ahn, Sang Hoon; Park, Do Joong; Kim, Hyung Ho.

In: World Journal of Gastroenterology, Vol. 20, No. 30, 14.08.2014, p. 10518-10524.

Research output: Contribution to journalArticle

Lee, Chang Min ; Jee, Ye Seob ; Lee, Ju Hee ; Son, Sang Yong ; Ahn, Sang Hoon ; Park, Do Joong ; Kim, Hyung Ho. / Length of negative resection margin does not affect local recurrence and survival in the patients with gastric cancer. In: World Journal of Gastroenterology. 2014 ; Vol. 20, No. 30. pp. 10518-10524.
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