Lid wiper epitheliopathy in patients with dry eye refractory to conventional medical treatment

Jungah Huh, In Ho Woo, Youngsub Eom, Su Yeon Kang, Hyo Myung Kim, Jong-Suk Song

Research output: Contribution to journalArticle

Abstract

Purpose: We evaluated the effects of lid wiper epitheliopathy on the clinical manifestations of dry eye in patients refractory to conventional medical treatment. Methods: Forty-six patients (46 eyes) completed the subjective Ocular Surface Disease Index (OSDI), and we obtained objective measures including the tear break-up time (TBUT), the National Eye Institute (NEI) corneal staining score, tear osmolarity, and lid wiper epitheliopathy as revealed on photographs taken using a yellow filter after fluorescein instillation. The images were graded using the Korb B protocol. Results: The mean OSDI score was 48.06 ± 21.19; 34 patients (73.9%) were had scores ≥33. Lid wiper epitheliopathy was evident in 41 (89.1%), and the epitheliopathy grade and OSDI score were correlated (r = 0.56, p < 0.01). The NEI score was also positively correlated with the OSDI score (r = 0.54, p < 0.01), but the mean value was low (1.59 ± 2.13). The OSDI score did not correlate significantly with either the TBUT or tear osmolarity (r = -0.16, p = 0.279; r = 0.16, p = 0.298, respectively). Conclusions: Lid wiper epitheliopathy was present in about 90% of patients with dry eye who visited our tertiary hospital, and a significant correlation was evident between the epitheliopathy grade and the OSDI score.

Original languageEnglish
Pages (from-to)718-723
Number of pages6
JournalJournal of Korean Ophthalmological Society
Volume59
Issue number8
DOIs
Publication statusPublished - 2018 Aug 1

Fingerprint

Eye Diseases
Tears
National Eye Institute (U.S.)
Osmolar Concentration
Eye Manifestations
Therapeutics
Fluorescein
Tertiary Care Centers
Staining and Labeling

Keywords

  • Correlation
  • Dry eye
  • Lid wiper epitheliopathy
  • Medical
  • Refractory

ASJC Scopus subject areas

  • Ophthalmology

Cite this

Lid wiper epitheliopathy in patients with dry eye refractory to conventional medical treatment. / Huh, Jungah; Woo, In Ho; Eom, Youngsub; Kang, Su Yeon; Kim, Hyo Myung; Song, Jong-Suk.

In: Journal of Korean Ophthalmological Society, Vol. 59, No. 8, 01.08.2018, p. 718-723.

Research output: Contribution to journalArticle

@article{bb19c6bb192f4017b8dbb67f181cd507,
title = "Lid wiper epitheliopathy in patients with dry eye refractory to conventional medical treatment",
abstract = "Purpose: We evaluated the effects of lid wiper epitheliopathy on the clinical manifestations of dry eye in patients refractory to conventional medical treatment. Methods: Forty-six patients (46 eyes) completed the subjective Ocular Surface Disease Index (OSDI), and we obtained objective measures including the tear break-up time (TBUT), the National Eye Institute (NEI) corneal staining score, tear osmolarity, and lid wiper epitheliopathy as revealed on photographs taken using a yellow filter after fluorescein instillation. The images were graded using the Korb B protocol. Results: The mean OSDI score was 48.06 ± 21.19; 34 patients (73.9{\%}) were had scores ≥33. Lid wiper epitheliopathy was evident in 41 (89.1{\%}), and the epitheliopathy grade and OSDI score were correlated (r = 0.56, p < 0.01). The NEI score was also positively correlated with the OSDI score (r = 0.54, p < 0.01), but the mean value was low (1.59 ± 2.13). The OSDI score did not correlate significantly with either the TBUT or tear osmolarity (r = -0.16, p = 0.279; r = 0.16, p = 0.298, respectively). Conclusions: Lid wiper epitheliopathy was present in about 90{\%} of patients with dry eye who visited our tertiary hospital, and a significant correlation was evident between the epitheliopathy grade and the OSDI score.",
keywords = "Correlation, Dry eye, Lid wiper epitheliopathy, Medical, Refractory",
author = "Jungah Huh and Woo, {In Ho} and Youngsub Eom and Kang, {Su Yeon} and Kim, {Hyo Myung} and Jong-Suk Song",
year = "2018",
month = "8",
day = "1",
doi = "10.3341/jkos.2018.59.8.718",
language = "English",
volume = "59",
pages = "718--723",
journal = "Journal of Korean Ophthalmological Society",
issn = "0378-6471",
publisher = "Korean Ophthalmological Society",
number = "8",

}

TY - JOUR

T1 - Lid wiper epitheliopathy in patients with dry eye refractory to conventional medical treatment

AU - Huh, Jungah

AU - Woo, In Ho

AU - Eom, Youngsub

AU - Kang, Su Yeon

AU - Kim, Hyo Myung

AU - Song, Jong-Suk

PY - 2018/8/1

Y1 - 2018/8/1

N2 - Purpose: We evaluated the effects of lid wiper epitheliopathy on the clinical manifestations of dry eye in patients refractory to conventional medical treatment. Methods: Forty-six patients (46 eyes) completed the subjective Ocular Surface Disease Index (OSDI), and we obtained objective measures including the tear break-up time (TBUT), the National Eye Institute (NEI) corneal staining score, tear osmolarity, and lid wiper epitheliopathy as revealed on photographs taken using a yellow filter after fluorescein instillation. The images were graded using the Korb B protocol. Results: The mean OSDI score was 48.06 ± 21.19; 34 patients (73.9%) were had scores ≥33. Lid wiper epitheliopathy was evident in 41 (89.1%), and the epitheliopathy grade and OSDI score were correlated (r = 0.56, p < 0.01). The NEI score was also positively correlated with the OSDI score (r = 0.54, p < 0.01), but the mean value was low (1.59 ± 2.13). The OSDI score did not correlate significantly with either the TBUT or tear osmolarity (r = -0.16, p = 0.279; r = 0.16, p = 0.298, respectively). Conclusions: Lid wiper epitheliopathy was present in about 90% of patients with dry eye who visited our tertiary hospital, and a significant correlation was evident between the epitheliopathy grade and the OSDI score.

AB - Purpose: We evaluated the effects of lid wiper epitheliopathy on the clinical manifestations of dry eye in patients refractory to conventional medical treatment. Methods: Forty-six patients (46 eyes) completed the subjective Ocular Surface Disease Index (OSDI), and we obtained objective measures including the tear break-up time (TBUT), the National Eye Institute (NEI) corneal staining score, tear osmolarity, and lid wiper epitheliopathy as revealed on photographs taken using a yellow filter after fluorescein instillation. The images were graded using the Korb B protocol. Results: The mean OSDI score was 48.06 ± 21.19; 34 patients (73.9%) were had scores ≥33. Lid wiper epitheliopathy was evident in 41 (89.1%), and the epitheliopathy grade and OSDI score were correlated (r = 0.56, p < 0.01). The NEI score was also positively correlated with the OSDI score (r = 0.54, p < 0.01), but the mean value was low (1.59 ± 2.13). The OSDI score did not correlate significantly with either the TBUT or tear osmolarity (r = -0.16, p = 0.279; r = 0.16, p = 0.298, respectively). Conclusions: Lid wiper epitheliopathy was present in about 90% of patients with dry eye who visited our tertiary hospital, and a significant correlation was evident between the epitheliopathy grade and the OSDI score.

KW - Correlation

KW - Dry eye

KW - Lid wiper epitheliopathy

KW - Medical

KW - Refractory

UR - http://www.scopus.com/inward/record.url?scp=85051750588&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85051750588&partnerID=8YFLogxK

U2 - 10.3341/jkos.2018.59.8.718

DO - 10.3341/jkos.2018.59.8.718

M3 - Article

AN - SCOPUS:85051750588

VL - 59

SP - 718

EP - 723

JO - Journal of Korean Ophthalmological Society

JF - Journal of Korean Ophthalmological Society

SN - 0378-6471

IS - 8

ER -