Abstract
We investigated the effect of IV lidocaine on the hemodynamic and bispectral index responses to induction of general anesthesia and endotracheal intubation. Forty patients (ASA I) were randomly allocated into 2 groups of 20 to receive normal saline or lidocaine 1.5 mg/kg IV 30 s after induction. Ninety seconds later, endotracheal intubation was performed. Systolic blood pressure, heart rate, and bispectral index were measured at baseline, 1 min after induction, at preintubation, and every minute until 5 min after endotracheal intubation. Bispectral index at 1 min after induction and preintubation in the lidocaine group were significantly lower compared with the control group (P < 0.05). Systolic blood pressure increased significantly at 1 and 2 min after intubation in the control group compared with the baseline value (P < 0.05) but did not increase significantly in the lidocaine group. Heart rate increased at 1 to 3 min in both groups (P < 0.05), but there was no significant difference between the two groups. One patient in the control group had recall of the procedure. We conclude that the administration of IV lidocaine (1.5 mg/kg) does not suppress the hypnotic response to endotracheal intubation.
| Original language | English |
|---|---|
| Pages (from-to) | 156-159 |
| Number of pages | 4 |
| Journal | Anesthesia and Analgesia |
| Volume | 102 |
| Issue number | 1 |
| DOIs | |
| Publication status | Published - 2006 Jan 1 |
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ASJC Scopus subject areas
- Anesthesiology and Pain Medicine
Cite this
Lidocaine does not prevent bispectral index increases in response to endotracheal intubation. / Kim, Woon Young; Lee, Yoon Sook; Ok, Se Jin; Chang, Moon Seok; Kim, Jae Hwan; Park, Young Cheol; Lim, Hae Ja.
In: Anesthesia and Analgesia, Vol. 102, No. 1, 01.01.2006, p. 156-159.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Lidocaine does not prevent bispectral index increases in response to endotracheal intubation
AU - Kim, Woon Young
AU - Lee, Yoon Sook
AU - Ok, Se Jin
AU - Chang, Moon Seok
AU - Kim, Jae Hwan
AU - Park, Young Cheol
AU - Lim, Hae Ja
PY - 2006/1/1
Y1 - 2006/1/1
N2 - We investigated the effect of IV lidocaine on the hemodynamic and bispectral index responses to induction of general anesthesia and endotracheal intubation. Forty patients (ASA I) were randomly allocated into 2 groups of 20 to receive normal saline or lidocaine 1.5 mg/kg IV 30 s after induction. Ninety seconds later, endotracheal intubation was performed. Systolic blood pressure, heart rate, and bispectral index were measured at baseline, 1 min after induction, at preintubation, and every minute until 5 min after endotracheal intubation. Bispectral index at 1 min after induction and preintubation in the lidocaine group were significantly lower compared with the control group (P < 0.05). Systolic blood pressure increased significantly at 1 and 2 min after intubation in the control group compared with the baseline value (P < 0.05) but did not increase significantly in the lidocaine group. Heart rate increased at 1 to 3 min in both groups (P < 0.05), but there was no significant difference between the two groups. One patient in the control group had recall of the procedure. We conclude that the administration of IV lidocaine (1.5 mg/kg) does not suppress the hypnotic response to endotracheal intubation.
AB - We investigated the effect of IV lidocaine on the hemodynamic and bispectral index responses to induction of general anesthesia and endotracheal intubation. Forty patients (ASA I) were randomly allocated into 2 groups of 20 to receive normal saline or lidocaine 1.5 mg/kg IV 30 s after induction. Ninety seconds later, endotracheal intubation was performed. Systolic blood pressure, heart rate, and bispectral index were measured at baseline, 1 min after induction, at preintubation, and every minute until 5 min after endotracheal intubation. Bispectral index at 1 min after induction and preintubation in the lidocaine group were significantly lower compared with the control group (P < 0.05). Systolic blood pressure increased significantly at 1 and 2 min after intubation in the control group compared with the baseline value (P < 0.05) but did not increase significantly in the lidocaine group. Heart rate increased at 1 to 3 min in both groups (P < 0.05), but there was no significant difference between the two groups. One patient in the control group had recall of the procedure. We conclude that the administration of IV lidocaine (1.5 mg/kg) does not suppress the hypnotic response to endotracheal intubation.
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U2 - 10.1213/01.ANE.0000184040.85956.98
DO - 10.1213/01.ANE.0000184040.85956.98
M3 - Article
VL - 102
SP - 156
EP - 159
JO - Current researches in anesthesia & analgesia
JF - Current researches in anesthesia & analgesia
SN - 0003-2999
IS - 1
ER -