Liver cirrhosis induced by porphyria cutanea tarda: A case report and review

Research output: Contribution to journalReview article

5 Citations (Scopus)

Abstract

Porphyria cutanea tarda (PCT) is a metabolic disorder that results in a decrease in uroporphyrinogen decarboxylase activity. It is characterized by photosensitivity, bullae formation, and skin pigmentation. There are four types of PCT: acquired, familial, toxic, and hepatoerythropoietic. Uroporphyrin levels are elevated in the urine of PCT patients. PCT can be differentiated from other porphyrias by its clinical characteristics and the porphyrin levels in the serum, erythrocytes, urine, and feces. This metabolic disorder can lead to liver dysfunction as well as histological changes such as fatty infiltration or hepatic fibrosis. PCT rarely manifests as liver cirrhosis. We report herein a case of PCT-induced liver cirrhosis that progressed to hepatic failure.

Original languageEnglish
Pages (from-to)551-555
Number of pages5
JournalGut and liver
Volume4
Issue number4
DOIs
Publication statusPublished - 2010 Dec

Keywords

  • Liver cirrhosis
  • Metabolic disorder
  • Porphyria cutanea tarda
  • Uroporphyrin

ASJC Scopus subject areas

  • Hepatology
  • Gastroenterology

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