Localized pulmonary alveolar proteinosis: Two case reports

Seon Jeong Oh, Ji Yung Choo, Ki Yeol Lee, Je Hyeong Kim, Suk Keu Yeom

Research output: Contribution to journalArticlepeer-review

3 Citations (Scopus)


Background: Pulmonary alveolar proteinosis (PAP) is a relatively rare disease characterized by abnormal accumulation of surfactantlike material in the alveolar spaces. The classic radiologic findings of PAP include bilateral, symmetric, diffuse ground-glass opacity (GGO) or consolidation. The most common computed tomography (CT) feature of PAP is widespread GGO with thickened interlobular septa, the so-called crazy-paving pattern, which strongly suggests the diagnosis.

Case Report: Here, we report the cases of two young male patients with unusual presentations of PAP. One patient showed localized PAP in the left lower lobe on CT images and the other patient presented with unilateral PAP involving the right lower lung field and recurrence in the same area with the same pattern as the initial manifestation.

Conclusion: In conclusion, it is important for radiologists to be aware of potential atypical imaging findings of PAP in order to provide a correct diagnosis. Along these lines, PAP can present as a solitary nodular lesion or unilateral focal lesion, and can recur in the same pattern and location.

Original languageEnglish
Pages (from-to)257-260
Number of pages4
JournalBalkan Medical Journal
Issue number3
Publication statusPublished - 2014
Externally publishedYes


  • CT
  • Localized
  • Pulmonary alveolar proteinosis

ASJC Scopus subject areas

  • Medicine(all)


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