Long-term clinical outcomes of catheter ablation in patients with atrial fibrillation predisposing to tachycardia-bradycardia syndrome: A long pause predicts implantation of a permanent pacemaker

Dong Hyeok Kim, Jong Il Choi, Kwang No Lee, Jinhee Ahn, Seung Young Roh, Dae In Lee, Jaemin Shim, Jin Seok Kim, Hong Euy Lim, Sang Weon Park, Young Hoon Kim

Research output: Contribution to journalArticlepeer-review

4 Citations (Scopus)

Abstract

Background: There is a controversy as to whether catheter ablation should be the first-line therapy for tachycardia-bradycardia syndrome (TBS) in patients with atrial fibrillation (AF). Methods: We aimed to investigate long-term clinical outcomes of catheter ablation in patients with TBS and AF. Among 145 consecutive patients who underwent catheter ablation of AF with TBS, 121 patients were studied. Results: Among 121 patients, 11 (9.1%) received implantation of a permanent pacemaker during a mean 21 months after ablation. Length of pause on termination of AF was significantly greater in patients who received pacemaker implantation after ablation than those who underwent ablation only (7.9 ± 3.5 vs. 5.1 ± 2.1 s, p < 0.001). Using a multivariate model, a long pause of 6.3 s or longer after termination of AF was associated with the requirement to implant a permanent pacemaker after ablation (HR 1.332, 95% CI 1.115-1.591, p = 0.002). Conclusion: This study suggests that, in patients with AF predisposing to TBS, long pause on termination of AF predicts the need to implant a permanent pacemaker after catheter ablation.

Original languageEnglish
Article number106
JournalBMC Cardiovascular Disorders
Volume18
Issue number1
DOIs
Publication statusPublished - 2018 May 30

Keywords

  • Atrial fibrillation
  • Bradycardia
  • Catheter ablation
  • Pacemaker
  • Tachycardia

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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