Long-term clinical outcomes of catheter ablation in patients with atrial fibrillation predisposing to tachycardia-bradycardia syndrome: A long pause predicts implantation of a permanent pacemaker

Dong Hyeok Kim, Jongil Choi, Kwang No Lee, Jinhee Ahn, Seung Young Roh, Dae In Lee, Jaemin Shim, Jin-Seok Kim, Hong Euy Lim, Sang Weon Park, Young Hoon Kim

Research output: Contribution to journalArticle

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Abstract

Background: There is a controversy as to whether catheter ablation should be the first-line therapy for tachycardia-bradycardia syndrome (TBS) in patients with atrial fibrillation (AF). Methods: We aimed to investigate long-term clinical outcomes of catheter ablation in patients with TBS and AF. Among 145 consecutive patients who underwent catheter ablation of AF with TBS, 121 patients were studied. Results: Among 121 patients, 11 (9.1%) received implantation of a permanent pacemaker during a mean 21 months after ablation. Length of pause on termination of AF was significantly greater in patients who received pacemaker implantation after ablation than those who underwent ablation only (7.9 ± 3.5 vs. 5.1 ± 2.1 s, p < 0.001). Using a multivariate model, a long pause of 6.3 s or longer after termination of AF was associated with the requirement to implant a permanent pacemaker after ablation (HR 1.332, 95% CI 1.115-1.591, p = 0.002). Conclusion: This study suggests that, in patients with AF predisposing to TBS, long pause on termination of AF predicts the need to implant a permanent pacemaker after catheter ablation.

Original languageEnglish
Article number106
JournalBMC Cardiovascular Disorders
Volume18
Issue number1
DOIs
Publication statusPublished - 2018 May 30

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Catheter Ablation
Bradycardia
Tachycardia
Atrial Fibrillation

Keywords

  • Atrial fibrillation
  • Bradycardia
  • Catheter ablation
  • Pacemaker
  • Tachycardia

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Long-term clinical outcomes of catheter ablation in patients with atrial fibrillation predisposing to tachycardia-bradycardia syndrome : A long pause predicts implantation of a permanent pacemaker. / Kim, Dong Hyeok; Choi, Jongil; Lee, Kwang No; Ahn, Jinhee; Roh, Seung Young; Lee, Dae In; Shim, Jaemin; Kim, Jin-Seok; Lim, Hong Euy; Park, Sang Weon; Kim, Young Hoon.

In: BMC Cardiovascular Disorders, Vol. 18, No. 1, 106, 30.05.2018.

Research output: Contribution to journalArticle

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AU - Lee, Kwang No

AU - Ahn, Jinhee

AU - Roh, Seung Young

AU - Lee, Dae In

AU - Shim, Jaemin

AU - Kim, Jin-Seok

AU - Lim, Hong Euy

AU - Park, Sang Weon

AU - Kim, Young Hoon

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AB - Background: There is a controversy as to whether catheter ablation should be the first-line therapy for tachycardia-bradycardia syndrome (TBS) in patients with atrial fibrillation (AF). Methods: We aimed to investigate long-term clinical outcomes of catheter ablation in patients with TBS and AF. Among 145 consecutive patients who underwent catheter ablation of AF with TBS, 121 patients were studied. Results: Among 121 patients, 11 (9.1%) received implantation of a permanent pacemaker during a mean 21 months after ablation. Length of pause on termination of AF was significantly greater in patients who received pacemaker implantation after ablation than those who underwent ablation only (7.9 ± 3.5 vs. 5.1 ± 2.1 s, p < 0.001). Using a multivariate model, a long pause of 6.3 s or longer after termination of AF was associated with the requirement to implant a permanent pacemaker after ablation (HR 1.332, 95% CI 1.115-1.591, p = 0.002). Conclusion: This study suggests that, in patients with AF predisposing to TBS, long pause on termination of AF predicts the need to implant a permanent pacemaker after catheter ablation.

KW - Atrial fibrillation

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KW - Tachycardia

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