Long-term outcome of capsule endoscopy in obscure gastrointestinal bleeding

A nationwide analysis

Yang Won Min, Jin Su Kim, Seong Woo Jeon, Yoon Tae Jeen, Jong Pil Im, Dae Young Cheung, Myung Gyu Choi, Jin Oh Kim, Kwang Jae Lee, Byong Duk Ye, Ki Nam Shim, Jeong Seop Moon, Ji Hyun Kim, Sung Pil Hong, Dong Kyung Chang

Research output: Contribution to journalArticle

40 Citations (Scopus)

Abstract

Background and study aims: The clinical impact of video capsule endoscopy (VCE) in patients with obscure gastrointestinal bleeding (OGIB) remains undetermined. The aim of this study was to evaluate the long-term clinical impact of VCE in patients with OGIB using a nationwide registry. Patients and methods: Data from 305 patients who underwent VCE for OGIB from 13 hospitals in Korea between January 2006 and March 2009 were analyzed. Prospectively collected VCE registry data were reviewed, and follow-up data were collected by chart review and telephone interviews with patients. Multivariate regression analyses using hazard ratios (HR) were performed to determine risk factors for rebleeding. Results: Significant findings were detected in 157 patients (51.5 %). After VCE, interventional treatment was performed in 36 patients (11.8 %). The overall rebleeding rate was 19.0 % during a mean (± SD) follow-up of 38.7 ± 26.4 months. Rebleeding rate did not differ by positive VCE results or application of interventional treatment. Multivariate analysis revealed that angiodysplasia (HR 1.82; 95 % confidence interval [CI] 1.04 - 3.20; P = 0.037) and duration of OGIB > 3 months (HR 1.64; 95 %CI 1.10 - 2.46; P = 0.016) were independent prognostic factors associated with rebleeding. In a subgroup analysis of patients taking anticoagulants, patients who discontinued drugs after VCE showed a lower rebleeding rate than those who did not discontinue this therapy (P = 0.019). Conclusions: VCE did not have a significant impact on the long-term outcome of patients with OGIB. Patients with angiodysplasia on VCE or OGIB > 3 months need to be closely followed even after interventional treatment. In patients who are taking anticoagulants, discontinuation of drugs is necessary in order to lower the risk of rebleeding.

Original languageEnglish
Pages (from-to)59-65
Number of pages7
JournalEndoscopy
Volume46
Issue number1
DOIs
Publication statusPublished - 2014 Jan 1

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Capsule Endoscopy
Hemorrhage
Angiodysplasia
Anticoagulants
Registries
Multivariate Analysis
Confidence Intervals
Therapeutics
Korea

ASJC Scopus subject areas

  • Gastroenterology

Cite this

Min, Y. W., Kim, J. S., Jeon, S. W., Jeen, Y. T., Im, J. P., Cheung, D. Y., ... Chang, D. K. (2014). Long-term outcome of capsule endoscopy in obscure gastrointestinal bleeding: A nationwide analysis. Endoscopy, 46(1), 59-65. https://doi.org/10.1055/s-0033-1358803

Long-term outcome of capsule endoscopy in obscure gastrointestinal bleeding : A nationwide analysis. / Min, Yang Won; Kim, Jin Su; Jeon, Seong Woo; Jeen, Yoon Tae; Im, Jong Pil; Cheung, Dae Young; Choi, Myung Gyu; Kim, Jin Oh; Lee, Kwang Jae; Ye, Byong Duk; Shim, Ki Nam; Moon, Jeong Seop; Kim, Ji Hyun; Hong, Sung Pil; Chang, Dong Kyung.

In: Endoscopy, Vol. 46, No. 1, 01.01.2014, p. 59-65.

Research output: Contribution to journalArticle

Min, YW, Kim, JS, Jeon, SW, Jeen, YT, Im, JP, Cheung, DY, Choi, MG, Kim, JO, Lee, KJ, Ye, BD, Shim, KN, Moon, JS, Kim, JH, Hong, SP & Chang, DK 2014, 'Long-term outcome of capsule endoscopy in obscure gastrointestinal bleeding: A nationwide analysis', Endoscopy, vol. 46, no. 1, pp. 59-65. https://doi.org/10.1055/s-0033-1358803
Min, Yang Won ; Kim, Jin Su ; Jeon, Seong Woo ; Jeen, Yoon Tae ; Im, Jong Pil ; Cheung, Dae Young ; Choi, Myung Gyu ; Kim, Jin Oh ; Lee, Kwang Jae ; Ye, Byong Duk ; Shim, Ki Nam ; Moon, Jeong Seop ; Kim, Ji Hyun ; Hong, Sung Pil ; Chang, Dong Kyung. / Long-term outcome of capsule endoscopy in obscure gastrointestinal bleeding : A nationwide analysis. In: Endoscopy. 2014 ; Vol. 46, No. 1. pp. 59-65.
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AU - Im, Jong Pil

AU - Cheung, Dae Young

AU - Choi, Myung Gyu

AU - Kim, Jin Oh

AU - Lee, Kwang Jae

AU - Ye, Byong Duk

AU - Shim, Ki Nam

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