Long-Term Outcome of Single-chamber atrial pacing compared with Dual-chamber pacing in patients with Sinus-node dysfunction and intact atrioventricular node conduction

Won Ho Kim, Boyoung Joung, Jaemin Shim, Jong Sung Park, Eui Seock Hwang, Hui Nam Pak, Sungsoon Kim, Moonhyoung Lee

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Purpose: The optimal pacing mode with either single chamber atrial pacemaker (AAI or AAIR) or dual chamber pacemaker (DDD or DDDR) is still not clear in sinus-node dysfunction (SND) and intact atrioventricular (AV) conduction. Materials and Methods: Patients who were implanted with permanent pacemaker using AAI(R) (n = 73) or DDD(R) (n = 113) were compared. Results: The baseline characteristics were comparable between the two groups, with a mean follow-up duration of 69 months. The incidence of death did not show statistical difference. However, the incidence of hospitalization for congestive heart failure (CHF) was significantly lower in the AAI(R) group (0%) than the DDD(R) group (8.8%, p = 0.03). Also, atrial fibrillation (AF) was found in 2.8% in the AAI(R) group, which was statistically different from 15.2% of patients in the DDD(R) group (p = 0.01). Four patients (5.5%) with AAI(R) developed AV block, and subsequently switched to DDD(R) pacing. The risk of AF was lower in the patients implanted with AAI(R) than those with DDD(R) [hazard ratio (HR), 0.84; 95% confidence interval, 0.72 to 0.97, p = 0.02]. Conclusion: In patients with SND and intact AV conduction, AAI(R) pacing can achieve a better clinical outcome in terms of occurrence of CHF and AF than DDD(R) pacing. These findings support AAI(R) pacing as the preferred pacing mode in patients with SND and intact AV conduction.

Original languageEnglish
Pages (from-to)832-837
Number of pages6
JournalYonsei Medical Journal
Volume51
Issue number6
DOIs
Publication statusPublished - 2010 Nov 1
Externally publishedYes

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Sick Sinus Syndrome
Dichlorodiphenyldichloroethane
Atrioventricular Node
Atrial Fibrillation
Heart Failure
Atrioventricular Block
Incidence
Hospitalization
Confidence Intervals

Keywords

  • Intact AV conduction
  • Sinus node dysfunction

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Long-Term Outcome of Single-chamber atrial pacing compared with Dual-chamber pacing in patients with Sinus-node dysfunction and intact atrioventricular node conduction. / Kim, Won Ho; Joung, Boyoung; Shim, Jaemin; Park, Jong Sung; Hwang, Eui Seock; Pak, Hui Nam; Kim, Sungsoon; Lee, Moonhyoung.

In: Yonsei Medical Journal, Vol. 51, No. 6, 01.11.2010, p. 832-837.

Research output: Contribution to journalArticle

Kim, Won Ho ; Joung, Boyoung ; Shim, Jaemin ; Park, Jong Sung ; Hwang, Eui Seock ; Pak, Hui Nam ; Kim, Sungsoon ; Lee, Moonhyoung. / Long-Term Outcome of Single-chamber atrial pacing compared with Dual-chamber pacing in patients with Sinus-node dysfunction and intact atrioventricular node conduction. In: Yonsei Medical Journal. 2010 ; Vol. 51, No. 6. pp. 832-837.
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abstract = "Purpose: The optimal pacing mode with either single chamber atrial pacemaker (AAI or AAIR) or dual chamber pacemaker (DDD or DDDR) is still not clear in sinus-node dysfunction (SND) and intact atrioventricular (AV) conduction. Materials and Methods: Patients who were implanted with permanent pacemaker using AAI(R) (n = 73) or DDD(R) (n = 113) were compared. Results: The baseline characteristics were comparable between the two groups, with a mean follow-up duration of 69 months. The incidence of death did not show statistical difference. However, the incidence of hospitalization for congestive heart failure (CHF) was significantly lower in the AAI(R) group (0{\%}) than the DDD(R) group (8.8{\%}, p = 0.03). Also, atrial fibrillation (AF) was found in 2.8{\%} in the AAI(R) group, which was statistically different from 15.2{\%} of patients in the DDD(R) group (p = 0.01). Four patients (5.5{\%}) with AAI(R) developed AV block, and subsequently switched to DDD(R) pacing. The risk of AF was lower in the patients implanted with AAI(R) than those with DDD(R) [hazard ratio (HR), 0.84; 95{\%} confidence interval, 0.72 to 0.97, p = 0.02]. Conclusion: In patients with SND and intact AV conduction, AAI(R) pacing can achieve a better clinical outcome in terms of occurrence of CHF and AF than DDD(R) pacing. These findings support AAI(R) pacing as the preferred pacing mode in patients with SND and intact AV conduction.",
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T1 - Long-Term Outcome of Single-chamber atrial pacing compared with Dual-chamber pacing in patients with Sinus-node dysfunction and intact atrioventricular node conduction

AU - Kim, Won Ho

AU - Joung, Boyoung

AU - Shim, Jaemin

AU - Park, Jong Sung

AU - Hwang, Eui Seock

AU - Pak, Hui Nam

AU - Kim, Sungsoon

AU - Lee, Moonhyoung

PY - 2010/11/1

Y1 - 2010/11/1

N2 - Purpose: The optimal pacing mode with either single chamber atrial pacemaker (AAI or AAIR) or dual chamber pacemaker (DDD or DDDR) is still not clear in sinus-node dysfunction (SND) and intact atrioventricular (AV) conduction. Materials and Methods: Patients who were implanted with permanent pacemaker using AAI(R) (n = 73) or DDD(R) (n = 113) were compared. Results: The baseline characteristics were comparable between the two groups, with a mean follow-up duration of 69 months. The incidence of death did not show statistical difference. However, the incidence of hospitalization for congestive heart failure (CHF) was significantly lower in the AAI(R) group (0%) than the DDD(R) group (8.8%, p = 0.03). Also, atrial fibrillation (AF) was found in 2.8% in the AAI(R) group, which was statistically different from 15.2% of patients in the DDD(R) group (p = 0.01). Four patients (5.5%) with AAI(R) developed AV block, and subsequently switched to DDD(R) pacing. The risk of AF was lower in the patients implanted with AAI(R) than those with DDD(R) [hazard ratio (HR), 0.84; 95% confidence interval, 0.72 to 0.97, p = 0.02]. Conclusion: In patients with SND and intact AV conduction, AAI(R) pacing can achieve a better clinical outcome in terms of occurrence of CHF and AF than DDD(R) pacing. These findings support AAI(R) pacing as the preferred pacing mode in patients with SND and intact AV conduction.

AB - Purpose: The optimal pacing mode with either single chamber atrial pacemaker (AAI or AAIR) or dual chamber pacemaker (DDD or DDDR) is still not clear in sinus-node dysfunction (SND) and intact atrioventricular (AV) conduction. Materials and Methods: Patients who were implanted with permanent pacemaker using AAI(R) (n = 73) or DDD(R) (n = 113) were compared. Results: The baseline characteristics were comparable between the two groups, with a mean follow-up duration of 69 months. The incidence of death did not show statistical difference. However, the incidence of hospitalization for congestive heart failure (CHF) was significantly lower in the AAI(R) group (0%) than the DDD(R) group (8.8%, p = 0.03). Also, atrial fibrillation (AF) was found in 2.8% in the AAI(R) group, which was statistically different from 15.2% of patients in the DDD(R) group (p = 0.01). Four patients (5.5%) with AAI(R) developed AV block, and subsequently switched to DDD(R) pacing. The risk of AF was lower in the patients implanted with AAI(R) than those with DDD(R) [hazard ratio (HR), 0.84; 95% confidence interval, 0.72 to 0.97, p = 0.02]. Conclusion: In patients with SND and intact AV conduction, AAI(R) pacing can achieve a better clinical outcome in terms of occurrence of CHF and AF than DDD(R) pacing. These findings support AAI(R) pacing as the preferred pacing mode in patients with SND and intact AV conduction.

KW - Intact AV conduction

KW - Sinus node dysfunction

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