Long-term predictive factors of major adverse cardiac events in patients with acute myocardial infarction complication by cardiogenic shock

Eun Hui Bae, Sang Yeob Lim, Myung Ho Jeong, Hyung Wook Park, Ji Hyun Lim, Young Joon Hong, Weon Kim, Ju Han Kim, Jeong Gwan Cho, Young Keun Ahn, Jong Chun Park, Soon Pal Suh, Byoung Hee Ahn, Sang Hyung Kim, Jung Chaee Kang

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Background: Cardiogenic shock (CS) after acute myocardial infarction (AMI) develops in 5 ∼ 10% of patients and it is associated with high mortality. The aim of this study is to assess the predictive factors of mortality for patients with AMI and CS. Methods: Two hundred fifty five AMI patients with CS (the mean age was 66.0±11.0 years, M:F=156:99) out of 1,268 AMI patients who admitted at Chonnam National University Hospital between July 2000 and June 2002 were analyzed according to the clinical characteristics, coronary angiographic findings and MACE during admission and for the 1-year clinical follow-up. Results: Among the enrolled patients, 129 patients survived without MACE (Group I, mean age 64.2±10.6 years, M:F=76:53), and 126 patients had MACE (Group II, mean age 68.1±10.0 years, M:F=80:46) during admission or during the 1-year follow-up period. There were significant differences in age between the Groups I and II (64.2±10.6 vs. 68.1±11.0 years, respectively, p=0.004) and the previous MI history (0 vs. 17.4%, respectively, p<0.001). The left ventricular ejection fraction (EF) was lower in Group II (Group I vs. II: 49.1±13.0 vs. 39.1±12.9%, p<0.001). The levels of troponin (Tn) I and C-reactive protein (CRP) were higher in Group II (Group I vs. II: 29.2±7.72 vs. 50.8±5.17 ng/dL, p=0.017, 3.8±0.48 vs. 9.9±1.21 mg/dL, p<0.001 respectively). Left main stem lesion (LMSL) was more common in Group II than in Group I (0.7% vs. 22.0%, respectively, p=0.004). In-hospital death was associated with low Thrombolysis In Myocardial Infarction (TIMI) flow after coronary revascularization. Conclusion: Old age, a previous MI history, high Tn and CRP, low EF and LMSL are associated with higher MACE for patients with AMI and CS. Coronary revascularization with TIMI 3 flow lowers the in-hospital mortality.

Original languageEnglish
Pages (from-to)8-14
Number of pages7
JournalKorean Journal of Internal Medicine
Volume20
Issue number1
Publication statusPublished - 2005 Mar 1
Externally publishedYes

Fingerprint

Cardiogenic Shock
Myocardial Infarction
Troponin C
C-Reactive Protein
History
Troponin I
Mortality
Hospital Mortality
Stroke Volume
Age Groups

Keywords

  • Coronary diseases
  • Myocardial infarction
  • Prognosis
  • Shock

ASJC Scopus subject areas

  • Internal Medicine

Cite this

Long-term predictive factors of major adverse cardiac events in patients with acute myocardial infarction complication by cardiogenic shock. / Bae, Eun Hui; Lim, Sang Yeob; Jeong, Myung Ho; Park, Hyung Wook; Lim, Ji Hyun; Hong, Young Joon; Kim, Weon; Kim, Ju Han; Cho, Jeong Gwan; Ahn, Young Keun; Park, Jong Chun; Suh, Soon Pal; Ahn, Byoung Hee; Kim, Sang Hyung; Kang, Jung Chaee.

In: Korean Journal of Internal Medicine, Vol. 20, No. 1, 01.03.2005, p. 8-14.

Research output: Contribution to journalArticle

Bae, EH, Lim, SY, Jeong, MH, Park, HW, Lim, JH, Hong, YJ, Kim, W, Kim, JH, Cho, JG, Ahn, YK, Park, JC, Suh, SP, Ahn, BH, Kim, SH & Kang, JC 2005, 'Long-term predictive factors of major adverse cardiac events in patients with acute myocardial infarction complication by cardiogenic shock', Korean Journal of Internal Medicine, vol. 20, no. 1, pp. 8-14.
Bae, Eun Hui ; Lim, Sang Yeob ; Jeong, Myung Ho ; Park, Hyung Wook ; Lim, Ji Hyun ; Hong, Young Joon ; Kim, Weon ; Kim, Ju Han ; Cho, Jeong Gwan ; Ahn, Young Keun ; Park, Jong Chun ; Suh, Soon Pal ; Ahn, Byoung Hee ; Kim, Sang Hyung ; Kang, Jung Chaee. / Long-term predictive factors of major adverse cardiac events in patients with acute myocardial infarction complication by cardiogenic shock. In: Korean Journal of Internal Medicine. 2005 ; Vol. 20, No. 1. pp. 8-14.
@article{7abc9c49aa9f411b96533376a0cdba71,
title = "Long-term predictive factors of major adverse cardiac events in patients with acute myocardial infarction complication by cardiogenic shock",
abstract = "Background: Cardiogenic shock (CS) after acute myocardial infarction (AMI) develops in 5 ∼ 10{\%} of patients and it is associated with high mortality. The aim of this study is to assess the predictive factors of mortality for patients with AMI and CS. Methods: Two hundred fifty five AMI patients with CS (the mean age was 66.0±11.0 years, M:F=156:99) out of 1,268 AMI patients who admitted at Chonnam National University Hospital between July 2000 and June 2002 were analyzed according to the clinical characteristics, coronary angiographic findings and MACE during admission and for the 1-year clinical follow-up. Results: Among the enrolled patients, 129 patients survived without MACE (Group I, mean age 64.2±10.6 years, M:F=76:53), and 126 patients had MACE (Group II, mean age 68.1±10.0 years, M:F=80:46) during admission or during the 1-year follow-up period. There were significant differences in age between the Groups I and II (64.2±10.6 vs. 68.1±11.0 years, respectively, p=0.004) and the previous MI history (0 vs. 17.4{\%}, respectively, p<0.001). The left ventricular ejection fraction (EF) was lower in Group II (Group I vs. II: 49.1±13.0 vs. 39.1±12.9{\%}, p<0.001). The levels of troponin (Tn) I and C-reactive protein (CRP) were higher in Group II (Group I vs. II: 29.2±7.72 vs. 50.8±5.17 ng/dL, p=0.017, 3.8±0.48 vs. 9.9±1.21 mg/dL, p<0.001 respectively). Left main stem lesion (LMSL) was more common in Group II than in Group I (0.7{\%} vs. 22.0{\%}, respectively, p=0.004). In-hospital death was associated with low Thrombolysis In Myocardial Infarction (TIMI) flow after coronary revascularization. Conclusion: Old age, a previous MI history, high Tn and CRP, low EF and LMSL are associated with higher MACE for patients with AMI and CS. Coronary revascularization with TIMI 3 flow lowers the in-hospital mortality.",
keywords = "Coronary diseases, Myocardial infarction, Prognosis, Shock",
author = "Bae, {Eun Hui} and Lim, {Sang Yeob} and Jeong, {Myung Ho} and Park, {Hyung Wook} and Lim, {Ji Hyun} and Hong, {Young Joon} and Weon Kim and Kim, {Ju Han} and Cho, {Jeong Gwan} and Ahn, {Young Keun} and Park, {Jong Chun} and Suh, {Soon Pal} and Ahn, {Byoung Hee} and Kim, {Sang Hyung} and Kang, {Jung Chaee}",
year = "2005",
month = "3",
day = "1",
language = "English",
volume = "20",
pages = "8--14",
journal = "Korean Journal of Internal Medicine",
issn = "0494-4712",
publisher = "Korean Association of Internal Medicine",
number = "1",

}

TY - JOUR

T1 - Long-term predictive factors of major adverse cardiac events in patients with acute myocardial infarction complication by cardiogenic shock

AU - Bae, Eun Hui

AU - Lim, Sang Yeob

AU - Jeong, Myung Ho

AU - Park, Hyung Wook

AU - Lim, Ji Hyun

AU - Hong, Young Joon

AU - Kim, Weon

AU - Kim, Ju Han

AU - Cho, Jeong Gwan

AU - Ahn, Young Keun

AU - Park, Jong Chun

AU - Suh, Soon Pal

AU - Ahn, Byoung Hee

AU - Kim, Sang Hyung

AU - Kang, Jung Chaee

PY - 2005/3/1

Y1 - 2005/3/1

N2 - Background: Cardiogenic shock (CS) after acute myocardial infarction (AMI) develops in 5 ∼ 10% of patients and it is associated with high mortality. The aim of this study is to assess the predictive factors of mortality for patients with AMI and CS. Methods: Two hundred fifty five AMI patients with CS (the mean age was 66.0±11.0 years, M:F=156:99) out of 1,268 AMI patients who admitted at Chonnam National University Hospital between July 2000 and June 2002 were analyzed according to the clinical characteristics, coronary angiographic findings and MACE during admission and for the 1-year clinical follow-up. Results: Among the enrolled patients, 129 patients survived without MACE (Group I, mean age 64.2±10.6 years, M:F=76:53), and 126 patients had MACE (Group II, mean age 68.1±10.0 years, M:F=80:46) during admission or during the 1-year follow-up period. There were significant differences in age between the Groups I and II (64.2±10.6 vs. 68.1±11.0 years, respectively, p=0.004) and the previous MI history (0 vs. 17.4%, respectively, p<0.001). The left ventricular ejection fraction (EF) was lower in Group II (Group I vs. II: 49.1±13.0 vs. 39.1±12.9%, p<0.001). The levels of troponin (Tn) I and C-reactive protein (CRP) were higher in Group II (Group I vs. II: 29.2±7.72 vs. 50.8±5.17 ng/dL, p=0.017, 3.8±0.48 vs. 9.9±1.21 mg/dL, p<0.001 respectively). Left main stem lesion (LMSL) was more common in Group II than in Group I (0.7% vs. 22.0%, respectively, p=0.004). In-hospital death was associated with low Thrombolysis In Myocardial Infarction (TIMI) flow after coronary revascularization. Conclusion: Old age, a previous MI history, high Tn and CRP, low EF and LMSL are associated with higher MACE for patients with AMI and CS. Coronary revascularization with TIMI 3 flow lowers the in-hospital mortality.

AB - Background: Cardiogenic shock (CS) after acute myocardial infarction (AMI) develops in 5 ∼ 10% of patients and it is associated with high mortality. The aim of this study is to assess the predictive factors of mortality for patients with AMI and CS. Methods: Two hundred fifty five AMI patients with CS (the mean age was 66.0±11.0 years, M:F=156:99) out of 1,268 AMI patients who admitted at Chonnam National University Hospital between July 2000 and June 2002 were analyzed according to the clinical characteristics, coronary angiographic findings and MACE during admission and for the 1-year clinical follow-up. Results: Among the enrolled patients, 129 patients survived without MACE (Group I, mean age 64.2±10.6 years, M:F=76:53), and 126 patients had MACE (Group II, mean age 68.1±10.0 years, M:F=80:46) during admission or during the 1-year follow-up period. There were significant differences in age between the Groups I and II (64.2±10.6 vs. 68.1±11.0 years, respectively, p=0.004) and the previous MI history (0 vs. 17.4%, respectively, p<0.001). The left ventricular ejection fraction (EF) was lower in Group II (Group I vs. II: 49.1±13.0 vs. 39.1±12.9%, p<0.001). The levels of troponin (Tn) I and C-reactive protein (CRP) were higher in Group II (Group I vs. II: 29.2±7.72 vs. 50.8±5.17 ng/dL, p=0.017, 3.8±0.48 vs. 9.9±1.21 mg/dL, p<0.001 respectively). Left main stem lesion (LMSL) was more common in Group II than in Group I (0.7% vs. 22.0%, respectively, p=0.004). In-hospital death was associated with low Thrombolysis In Myocardial Infarction (TIMI) flow after coronary revascularization. Conclusion: Old age, a previous MI history, high Tn and CRP, low EF and LMSL are associated with higher MACE for patients with AMI and CS. Coronary revascularization with TIMI 3 flow lowers the in-hospital mortality.

KW - Coronary diseases

KW - Myocardial infarction

KW - Prognosis

KW - Shock

UR - http://www.scopus.com/inward/record.url?scp=21144452531&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=21144452531&partnerID=8YFLogxK

M3 - Article

VL - 20

SP - 8

EP - 14

JO - Korean Journal of Internal Medicine

JF - Korean Journal of Internal Medicine

SN - 0494-4712

IS - 1

ER -