Long-term results of percutaneous ethanol injection for the treatment of hepatocellular carcinoma in Korea

Mi Sung Yon, Dongil Choi, Hyo K. Lim, Jae Lee Won, Hoon Kim Seung, Ju Kim Min, Woon Paik Seung, Chul Yoo Byung, Cheol Koh Kwang, Hyoek Lee Joon, Seok Choi Moon

Research output: Contribution to journalArticle

20 Citations (Scopus)

Abstract

Objective: To evaluate the long-term follow-up results of percutaneous ethanol injection (PEI) for the treatment of hepatocellular carcinoma (HCC) in Korea. Materials and Methods: Sixty-eight nodular HCCs initially detected in 64 patients, were subjected to US-guided PEI as a first-line treatment. Long-term survival rates, local tumor progression rates, and complications were evaluated, as were the influences of tumor size and Child-Pugh class on these variables. Results: No major complications occurred. The overall survival rates of the 64 patients at three and five years were 71% and 39%, and their cancer-free survival rates were 22% and 15%, respectively. The overall survival rate of patients with a small HCC (≤ 2 cm) was significantly higher (p = 0.014) than that of patients with a medium-sized HCC (≤ 2 cm). The overall survival rate of patients with Child-Pugh class A was significantly higher (p = 0.049) than that of patients with Child-Pugh class B. Of 59 cases with no residual tumor, local tumor progression was observed in ablation zones in 18, and this was not found to be significantly influenced by tumor size or Child-Pugh class. Conclusion: The results of our investigation of the long-term survival rates of PEI in HCC patients in Korea (a hepatitis B virus-endemic area) were consistent with those reported previously in hepatitis C endemic areas. Patients with a smaller tumor or a better liver function exhibited superior survival rates.

Original languageEnglish
Pages (from-to)187-192
Number of pages6
JournalKorean journal of radiology
Volume7
Issue number3
Publication statusPublished - 2006

Keywords

  • Alcohol ablation
  • Liver neoplasms, therapy
  • Liver, neoplasms

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

Fingerprint Dive into the research topics of 'Long-term results of percutaneous ethanol injection for the treatment of hepatocellular carcinoma in Korea'. Together they form a unique fingerprint.

  • Cite this

    Yon, M. S., Choi, D., Lim, H. K., Won, J. L., Seung, H. K., Min, J. K., Seung, W. P., Byung, C. Y., Kwang, C. K., Joon, H. L., & Moon, S. C. (2006). Long-term results of percutaneous ethanol injection for the treatment of hepatocellular carcinoma in Korea. Korean journal of radiology, 7(3), 187-192.