Longitudinal Deep-Brain Imaging through an Intact Skull Using a Label-Free Reflection Matrix Microscopy

Yongwoo Kwon, Seokchan Yoon, Jin Hee Hong, Hojun Lee, Wonshik Choi

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

We implemented a label-free reflection matrix microscopy system using a 1.3-μm wavelength pulsed laser and conducted in vivo imaging of a 3- to 10-week-old mouse brain with an intact skull. The myelination processes at the early developmental stages were observed up to the cortical layer IV with the ideal diffraction-limited resolution of 650 nm.

Original languageEnglish
Title of host publicationCLEO
Subtitle of host publicationApplications and Technology, A and T 2022
PublisherOptica Publishing Group (formerly OSA)
ISBN (Electronic)9781957171050
Publication statusPublished - 2022
EventCLEO: Applications and Technology, A and T 2022 - San Jose, United States
Duration: 2022 May 152022 May 20

Publication series

NameOptics InfoBase Conference Papers

Conference

ConferenceCLEO: Applications and Technology, A and T 2022
Country/TerritoryUnited States
CitySan Jose
Period22/5/1522/5/20

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Mechanics of Materials

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