Longitudinal relationship between physical activity and cardiometabolic factors in overweight and obese adults

Jina Choo, Okan U. Elci, Kyeongra Yang, Melanie W. Turk, Mindi A. Styn, Susan M. Sereika, Edvin Music, Lora E. Burke

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

Few studies have reported longitudinal relationships between physical activity (PA) and cardiometabolic risk factors over time using repeated assessments in overweight or obese adults. We conducted a longitudinal study in 127 participants (81% with body mass index > 30 kg/m2) who completed a 12-month behavioral intervention for weight loss between 2003 and 2005 in Pittsburgh, PA, USA. Using absolute change scores from baseline to each time point (i.e., 6 and 12 months) for all studied variables (Δ = time point - baseline), we performed mixed effects modeling to examine relationships between PA and cardiometabolic risk factors, after adjusting for body weight, energy intake and other covariates (i.e., age, gender, and ethnicity). PA was assessed as energy expenditure (kcal/week) using the Paffenbarger activity questionnaire. Over the 12-month period, energy expenditure increased (Δ1,370 kcal/week at 6 months vs. Δ886 kcal/week at 12 months); body weight decreased (Δ8.9 kg at 6 months vs. Δ8.4 kg at 12 months). The average increase in energy expenditure over 12 months was significantly and independently related to reductions in total cholesterol (F = 6.25, p = 0.013), low-density lipoprotein cholesterol (LDL-C) (F = 5.08, p = 0.025) and fasting blood glucose (F = 5.10, p = 0.025), but not to other risk factors (i.e., fasting insulin, high-density lipoprotein cholesterol, triglycerides, and waist circumference). In conclusion, among overweight and obese adults undergoing a weight loss intervention, increased energy expenditure over 12 months may improve total cholesterol and LDL-C, important coronary risk factors, and fasting blood glucose, a metabolic risk factor.

Original languageEnglish
Pages (from-to)329-336
Number of pages8
JournalEuropean Journal of Applied Physiology
Volume108
Issue number2
DOIs
Publication statusPublished - 2010 Jan 1

Fingerprint

Energy Metabolism
Exercise
Fasting
LDL Cholesterol
Blood Glucose
Weight Loss
Cholesterol
Body Weight
Waist Circumference
Energy Intake
HDL Cholesterol
Longitudinal Studies
Triglycerides
Body Mass Index
Insulin

Keywords

  • Lipids
  • Longitudinal studies
  • Obesity
  • Physical activity
  • Weight loss

ASJC Scopus subject areas

  • Orthopedics and Sports Medicine
  • Physiology (medical)
  • Public Health, Environmental and Occupational Health

Cite this

Longitudinal relationship between physical activity and cardiometabolic factors in overweight and obese adults. / Choo, Jina; Elci, Okan U.; Yang, Kyeongra; Turk, Melanie W.; Styn, Mindi A.; Sereika, Susan M.; Music, Edvin; Burke, Lora E.

In: European Journal of Applied Physiology, Vol. 108, No. 2, 01.01.2010, p. 329-336.

Research output: Contribution to journalArticle

Choo, Jina ; Elci, Okan U. ; Yang, Kyeongra ; Turk, Melanie W. ; Styn, Mindi A. ; Sereika, Susan M. ; Music, Edvin ; Burke, Lora E. / Longitudinal relationship between physical activity and cardiometabolic factors in overweight and obese adults. In: European Journal of Applied Physiology. 2010 ; Vol. 108, No. 2. pp. 329-336.
@article{de76c271073943fa94c6b85af63d2abf,
title = "Longitudinal relationship between physical activity and cardiometabolic factors in overweight and obese adults",
abstract = "Few studies have reported longitudinal relationships between physical activity (PA) and cardiometabolic risk factors over time using repeated assessments in overweight or obese adults. We conducted a longitudinal study in 127 participants (81{\%} with body mass index > 30 kg/m2) who completed a 12-month behavioral intervention for weight loss between 2003 and 2005 in Pittsburgh, PA, USA. Using absolute change scores from baseline to each time point (i.e., 6 and 12 months) for all studied variables (Δ = time point - baseline), we performed mixed effects modeling to examine relationships between PA and cardiometabolic risk factors, after adjusting for body weight, energy intake and other covariates (i.e., age, gender, and ethnicity). PA was assessed as energy expenditure (kcal/week) using the Paffenbarger activity questionnaire. Over the 12-month period, energy expenditure increased (Δ1,370 kcal/week at 6 months vs. Δ886 kcal/week at 12 months); body weight decreased (Δ8.9 kg at 6 months vs. Δ8.4 kg at 12 months). The average increase in energy expenditure over 12 months was significantly and independently related to reductions in total cholesterol (F = 6.25, p = 0.013), low-density lipoprotein cholesterol (LDL-C) (F = 5.08, p = 0.025) and fasting blood glucose (F = 5.10, p = 0.025), but not to other risk factors (i.e., fasting insulin, high-density lipoprotein cholesterol, triglycerides, and waist circumference). In conclusion, among overweight and obese adults undergoing a weight loss intervention, increased energy expenditure over 12 months may improve total cholesterol and LDL-C, important coronary risk factors, and fasting blood glucose, a metabolic risk factor.",
keywords = "Lipids, Longitudinal studies, Obesity, Physical activity, Weight loss",
author = "Jina Choo and Elci, {Okan U.} and Kyeongra Yang and Turk, {Melanie W.} and Styn, {Mindi A.} and Sereika, {Susan M.} and Edvin Music and Burke, {Lora E.}",
year = "2010",
month = "1",
day = "1",
doi = "10.1007/s00421-009-1203-6",
language = "English",
volume = "108",
pages = "329--336",
journal = "European Journal of Applied Physiology",
issn = "1439-6319",
publisher = "Springer Verlag",
number = "2",

}

TY - JOUR

T1 - Longitudinal relationship between physical activity and cardiometabolic factors in overweight and obese adults

AU - Choo, Jina

AU - Elci, Okan U.

AU - Yang, Kyeongra

AU - Turk, Melanie W.

AU - Styn, Mindi A.

AU - Sereika, Susan M.

AU - Music, Edvin

AU - Burke, Lora E.

PY - 2010/1/1

Y1 - 2010/1/1

N2 - Few studies have reported longitudinal relationships between physical activity (PA) and cardiometabolic risk factors over time using repeated assessments in overweight or obese adults. We conducted a longitudinal study in 127 participants (81% with body mass index > 30 kg/m2) who completed a 12-month behavioral intervention for weight loss between 2003 and 2005 in Pittsburgh, PA, USA. Using absolute change scores from baseline to each time point (i.e., 6 and 12 months) for all studied variables (Δ = time point - baseline), we performed mixed effects modeling to examine relationships between PA and cardiometabolic risk factors, after adjusting for body weight, energy intake and other covariates (i.e., age, gender, and ethnicity). PA was assessed as energy expenditure (kcal/week) using the Paffenbarger activity questionnaire. Over the 12-month period, energy expenditure increased (Δ1,370 kcal/week at 6 months vs. Δ886 kcal/week at 12 months); body weight decreased (Δ8.9 kg at 6 months vs. Δ8.4 kg at 12 months). The average increase in energy expenditure over 12 months was significantly and independently related to reductions in total cholesterol (F = 6.25, p = 0.013), low-density lipoprotein cholesterol (LDL-C) (F = 5.08, p = 0.025) and fasting blood glucose (F = 5.10, p = 0.025), but not to other risk factors (i.e., fasting insulin, high-density lipoprotein cholesterol, triglycerides, and waist circumference). In conclusion, among overweight and obese adults undergoing a weight loss intervention, increased energy expenditure over 12 months may improve total cholesterol and LDL-C, important coronary risk factors, and fasting blood glucose, a metabolic risk factor.

AB - Few studies have reported longitudinal relationships between physical activity (PA) and cardiometabolic risk factors over time using repeated assessments in overweight or obese adults. We conducted a longitudinal study in 127 participants (81% with body mass index > 30 kg/m2) who completed a 12-month behavioral intervention for weight loss between 2003 and 2005 in Pittsburgh, PA, USA. Using absolute change scores from baseline to each time point (i.e., 6 and 12 months) for all studied variables (Δ = time point - baseline), we performed mixed effects modeling to examine relationships between PA and cardiometabolic risk factors, after adjusting for body weight, energy intake and other covariates (i.e., age, gender, and ethnicity). PA was assessed as energy expenditure (kcal/week) using the Paffenbarger activity questionnaire. Over the 12-month period, energy expenditure increased (Δ1,370 kcal/week at 6 months vs. Δ886 kcal/week at 12 months); body weight decreased (Δ8.9 kg at 6 months vs. Δ8.4 kg at 12 months). The average increase in energy expenditure over 12 months was significantly and independently related to reductions in total cholesterol (F = 6.25, p = 0.013), low-density lipoprotein cholesterol (LDL-C) (F = 5.08, p = 0.025) and fasting blood glucose (F = 5.10, p = 0.025), but not to other risk factors (i.e., fasting insulin, high-density lipoprotein cholesterol, triglycerides, and waist circumference). In conclusion, among overweight and obese adults undergoing a weight loss intervention, increased energy expenditure over 12 months may improve total cholesterol and LDL-C, important coronary risk factors, and fasting blood glucose, a metabolic risk factor.

KW - Lipids

KW - Longitudinal studies

KW - Obesity

KW - Physical activity

KW - Weight loss

UR - http://www.scopus.com/inward/record.url?scp=76449118107&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=76449118107&partnerID=8YFLogxK

U2 - 10.1007/s00421-009-1203-6

DO - 10.1007/s00421-009-1203-6

M3 - Article

C2 - 19806358

AN - SCOPUS:76449118107

VL - 108

SP - 329

EP - 336

JO - European Journal of Applied Physiology

JF - European Journal of Applied Physiology

SN - 1439-6319

IS - 2

ER -