TY - GEN
T1 - Low-intensity focused ultrasound stimulator using focal depth controller for improved targeting in neuromuscular rehabilitation
AU - Oh, Sungjin
AU - Kim, Dong Hwee
AU - Youn, Inchan
N1 - Funding Information:
ACKNOWLEDGMENT This research was supported by the Korea Health Technology R&D Project through the Korea Health Industry Development Institute (KHIDI), funded by the Ministry of Health & Welfare (HI14C3477). This research was also supported by the Next-Generation Medical Device Development Program for Newly Created Market of the National Research Foundation (NRF), funded by the Ministry of Science, ICT and Future Planning (2015M3D5A1066100).
Funding Information:
This research was supported by the Korea Health Technology R&D Project through the Korea Health Industry Development Institute (KHIDI), funded by the Ministry of Health & Welfare (HI14C3477). This research was also supported by the Next-Generation Medical Device Development Program for Newly Created Market of the National Research Foundation (NRF), funded by the Ministry of Science, ICT and Future Planning (2015M3D5A1066100).
Publisher Copyright:
© 2017 IEEE.
PY - 2017/9/13
Y1 - 2017/9/13
N2 - Low-intensity ultrasound can be used for noninvasive neuromuscular stimulation to enhance the recovery of injured peripheral nerves and muscles. In order to improve the stimulation efficiency, focused ultrasound (FUS) with a high energy density should be used. Because the FUS is concentrated at a miniaturized focal area, deliberate targeting with focal depth control is required to achieve the accurate stimulation. In this study, a low-intensity focused ultrasound (LIFU) stimulator with a focal depth controller is presented as an effective ultrasound stimulation system for the neuromuscular rehabilitation. In the developed stimulator, the target depth is adjusted by the focal depth controller with the brief structure. The experimental results show that the developed stimulator can generate the high quality LIFU stimulation with the spatial average-pulse average intensity (ISAPA) of 496 mW/cm2, which is sufficient to improve the rehabilitation of injured peripheral nerves and muscles. In the in vivo experiment, a rat's sciatic nerve was successfully targeted by the developed stimulator. These results indicate that the developed stimulator can be used to improve the quality of the ultrasound stimulation for neuromuscular rehabilitation by targeting a specific area.
AB - Low-intensity ultrasound can be used for noninvasive neuromuscular stimulation to enhance the recovery of injured peripheral nerves and muscles. In order to improve the stimulation efficiency, focused ultrasound (FUS) with a high energy density should be used. Because the FUS is concentrated at a miniaturized focal area, deliberate targeting with focal depth control is required to achieve the accurate stimulation. In this study, a low-intensity focused ultrasound (LIFU) stimulator with a focal depth controller is presented as an effective ultrasound stimulation system for the neuromuscular rehabilitation. In the developed stimulator, the target depth is adjusted by the focal depth controller with the brief structure. The experimental results show that the developed stimulator can generate the high quality LIFU stimulation with the spatial average-pulse average intensity (ISAPA) of 496 mW/cm2, which is sufficient to improve the rehabilitation of injured peripheral nerves and muscles. In the in vivo experiment, a rat's sciatic nerve was successfully targeted by the developed stimulator. These results indicate that the developed stimulator can be used to improve the quality of the ultrasound stimulation for neuromuscular rehabilitation by targeting a specific area.
UR - http://www.scopus.com/inward/record.url?scp=85032220550&partnerID=8YFLogxK
U2 - 10.1109/EMBC.2017.8036799
DO - 10.1109/EMBC.2017.8036799
M3 - Conference contribution
C2 - 29059847
AN - SCOPUS:85032220550
T3 - Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS
SP - 209
EP - 212
BT - 2017 39th Annual International Conference of the IEEE Engineering in Medicine and Biology Society
PB - Institute of Electrical and Electronics Engineers Inc.
T2 - 39th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2017
Y2 - 11 July 2017 through 15 July 2017
ER -