Low level of immunity against hepatitis A among Korean adolescents

Vaccination rate and related factors

Jung Yeon Heo, Joon-Young Song, Ji Yun Noh, Yu Bin Seo, In Sun Kim, Wonseok Choi, Woo Joo Kim, Geum-Joon Cho, Taik Gun Hwang, Hee-Jin Cheong

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Background: We evaluated the current vaccination rate and immunity in the Korean adolescent population and analyzed their parents' attitudes toward hepatitis A virus (HAV) vaccination. Methods: Between March and April 2011, sera were collected for immunoglobulin (Ig) G anti-HAV testing from students in their first year of high school from 12 different high schools located in southwestern Seoul. Simultaneously, questionnaires were given to the parents of the students to evaluate factors related to HAV vaccination, including demographics, HAV vaccination status, reason for getting the vaccination, and awareness regarding HAV. Results: Sera from 2,879 subjects and questionnaires from their parents were collected. The HAV vaccination rate among adolescents aged between 14 and 17 years was 18.9%, and the seroprevalence was 15.4%. Among subjects who reported receiving the HAV vaccination, the IgG anti-HAV seropositivity rate was only 42.2%. For subjects who were not vaccinated, the IgG anti-HAV seropositivity rate was 9.1%. The most significant reason for receiving the vaccination was recommendation from health care providers; the most important source of information regarding the vaccination was public health organizations. Conclusion: HAV vaccination rate and anti-HAV seroprevalence in Korean adolescents was low; the seropositivity rate in the vaccinated group was lower than expected. Actively recommending HAV vaccination in this group is required, and routine, nationwide, government-sponsored vaccination of adolescents against HAV should be considered.

Original languageEnglish
JournalAmerican Journal of Infection Control
Volume41
Issue number10
DOIs
Publication statusPublished - 2013 Oct 1

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Hepatitis A virus
Hepatitis A
Immunity
Vaccination
Parents
Seroepidemiologic Studies
Students
Immunization Programs
Serum
Health Personnel

Keywords

  • Epidemiology
  • Hepatitis A virus
  • Seroprevalence

ASJC Scopus subject areas

  • Infectious Diseases
  • Public Health, Environmental and Occupational Health
  • Epidemiology
  • Health Policy

Cite this

@article{3ca1da16cf3343eeb463083fbbb9cf88,
title = "Low level of immunity against hepatitis A among Korean adolescents: Vaccination rate and related factors",
abstract = "Background: We evaluated the current vaccination rate and immunity in the Korean adolescent population and analyzed their parents' attitudes toward hepatitis A virus (HAV) vaccination. Methods: Between March and April 2011, sera were collected for immunoglobulin (Ig) G anti-HAV testing from students in their first year of high school from 12 different high schools located in southwestern Seoul. Simultaneously, questionnaires were given to the parents of the students to evaluate factors related to HAV vaccination, including demographics, HAV vaccination status, reason for getting the vaccination, and awareness regarding HAV. Results: Sera from 2,879 subjects and questionnaires from their parents were collected. The HAV vaccination rate among adolescents aged between 14 and 17 years was 18.9{\%}, and the seroprevalence was 15.4{\%}. Among subjects who reported receiving the HAV vaccination, the IgG anti-HAV seropositivity rate was only 42.2{\%}. For subjects who were not vaccinated, the IgG anti-HAV seropositivity rate was 9.1{\%}. The most significant reason for receiving the vaccination was recommendation from health care providers; the most important source of information regarding the vaccination was public health organizations. Conclusion: HAV vaccination rate and anti-HAV seroprevalence in Korean adolescents was low; the seropositivity rate in the vaccinated group was lower than expected. Actively recommending HAV vaccination in this group is required, and routine, nationwide, government-sponsored vaccination of adolescents against HAV should be considered.",
keywords = "Epidemiology, Hepatitis A virus, Seroprevalence",
author = "Heo, {Jung Yeon} and Joon-Young Song and Noh, {Ji Yun} and Seo, {Yu Bin} and Kim, {In Sun} and Wonseok Choi and Kim, {Woo Joo} and Geum-Joon Cho and Hwang, {Taik Gun} and Hee-Jin Cheong",
year = "2013",
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language = "English",
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TY - JOUR

T1 - Low level of immunity against hepatitis A among Korean adolescents

T2 - Vaccination rate and related factors

AU - Heo, Jung Yeon

AU - Song, Joon-Young

AU - Noh, Ji Yun

AU - Seo, Yu Bin

AU - Kim, In Sun

AU - Choi, Wonseok

AU - Kim, Woo Joo

AU - Cho, Geum-Joon

AU - Hwang, Taik Gun

AU - Cheong, Hee-Jin

PY - 2013/10/1

Y1 - 2013/10/1

N2 - Background: We evaluated the current vaccination rate and immunity in the Korean adolescent population and analyzed their parents' attitudes toward hepatitis A virus (HAV) vaccination. Methods: Between March and April 2011, sera were collected for immunoglobulin (Ig) G anti-HAV testing from students in their first year of high school from 12 different high schools located in southwestern Seoul. Simultaneously, questionnaires were given to the parents of the students to evaluate factors related to HAV vaccination, including demographics, HAV vaccination status, reason for getting the vaccination, and awareness regarding HAV. Results: Sera from 2,879 subjects and questionnaires from their parents were collected. The HAV vaccination rate among adolescents aged between 14 and 17 years was 18.9%, and the seroprevalence was 15.4%. Among subjects who reported receiving the HAV vaccination, the IgG anti-HAV seropositivity rate was only 42.2%. For subjects who were not vaccinated, the IgG anti-HAV seropositivity rate was 9.1%. The most significant reason for receiving the vaccination was recommendation from health care providers; the most important source of information regarding the vaccination was public health organizations. Conclusion: HAV vaccination rate and anti-HAV seroprevalence in Korean adolescents was low; the seropositivity rate in the vaccinated group was lower than expected. Actively recommending HAV vaccination in this group is required, and routine, nationwide, government-sponsored vaccination of adolescents against HAV should be considered.

AB - Background: We evaluated the current vaccination rate and immunity in the Korean adolescent population and analyzed their parents' attitudes toward hepatitis A virus (HAV) vaccination. Methods: Between March and April 2011, sera were collected for immunoglobulin (Ig) G anti-HAV testing from students in their first year of high school from 12 different high schools located in southwestern Seoul. Simultaneously, questionnaires were given to the parents of the students to evaluate factors related to HAV vaccination, including demographics, HAV vaccination status, reason for getting the vaccination, and awareness regarding HAV. Results: Sera from 2,879 subjects and questionnaires from their parents were collected. The HAV vaccination rate among adolescents aged between 14 and 17 years was 18.9%, and the seroprevalence was 15.4%. Among subjects who reported receiving the HAV vaccination, the IgG anti-HAV seropositivity rate was only 42.2%. For subjects who were not vaccinated, the IgG anti-HAV seropositivity rate was 9.1%. The most significant reason for receiving the vaccination was recommendation from health care providers; the most important source of information regarding the vaccination was public health organizations. Conclusion: HAV vaccination rate and anti-HAV seroprevalence in Korean adolescents was low; the seropositivity rate in the vaccinated group was lower than expected. Actively recommending HAV vaccination in this group is required, and routine, nationwide, government-sponsored vaccination of adolescents against HAV should be considered.

KW - Epidemiology

KW - Hepatitis A virus

KW - Seroprevalence

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