Lymphocytic hypophysitis in a patient with systemic lupus erythematosus

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

A case of lymphocytic hypophysitis in a patient with systemic lupus erythematosus is described. A 20-year-old woman was admitted to our hospital with generalized myalgia and facial rash in May 1998. The patient had a medical history, physical examination, and laboratory findings compatible with systemic lupus erythematosus (SLE). Headache and nausea had developed 3 months previously and worsened over the following months. Hormonal investigation showed hypopituitarism except for prolactin. A magnetic resonance image of the brain showed a mass lesion in the pituitary fossa. A trans-sphenoidal surgical procedure was performed which revealed a dark- yellowish hematoma. Microscopic examination showed diffuse infiltration of lymphocytes and plasma cells with fibrosis in the anterior pituitary. Post- operatively the patient's headaches and nausea resolved. This indicates that lymphocytic hypophysitis may be associated with SLE.

Original languageEnglish
Pages (from-to)78-80
Number of pages3
JournalClinical and Experimental Rheumatology
Volume18
Issue number1
Publication statusPublished - 2000 Feb 29

Fingerprint

Systemic Lupus Erythematosus
Nausea
Headache
Hypopituitarism
Myalgia
Plasma Cells
Exanthema
Hematoma
Prolactin
Physical Examination
Fibrosis
Magnetic Resonance Spectroscopy
Lymphocytes
Brain
Autoimmune Hypophysitis

Keywords

  • Lymphocytic hypophysitis
  • Systemic lupus erythematosus

ASJC Scopus subject areas

  • Rheumatology
  • Immunology and Allergy
  • Immunology

Cite this

Lymphocytic hypophysitis in a patient with systemic lupus erythematosus. / Ji, Jong Dae; Lee, S. Y.; Choi, Sungjae; Lee, Young Ho; Song, Gwan Gyu.

In: Clinical and Experimental Rheumatology, Vol. 18, No. 1, 29.02.2000, p. 78-80.

Research output: Contribution to journalArticle

@article{b845e1fa00614050b6d9c91c5a8f2eee,
title = "Lymphocytic hypophysitis in a patient with systemic lupus erythematosus",
abstract = "A case of lymphocytic hypophysitis in a patient with systemic lupus erythematosus is described. A 20-year-old woman was admitted to our hospital with generalized myalgia and facial rash in May 1998. The patient had a medical history, physical examination, and laboratory findings compatible with systemic lupus erythematosus (SLE). Headache and nausea had developed 3 months previously and worsened over the following months. Hormonal investigation showed hypopituitarism except for prolactin. A magnetic resonance image of the brain showed a mass lesion in the pituitary fossa. A trans-sphenoidal surgical procedure was performed which revealed a dark- yellowish hematoma. Microscopic examination showed diffuse infiltration of lymphocytes and plasma cells with fibrosis in the anterior pituitary. Post- operatively the patient's headaches and nausea resolved. This indicates that lymphocytic hypophysitis may be associated with SLE.",
keywords = "Lymphocytic hypophysitis, Systemic lupus erythematosus",
author = "Ji, {Jong Dae} and Lee, {S. Y.} and Sungjae Choi and Lee, {Young Ho} and Song, {Gwan Gyu}",
year = "2000",
month = "2",
day = "29",
language = "English",
volume = "18",
pages = "78--80",
journal = "Clinical and Experimental Rheumatology",
issn = "0392-856X",
publisher = "Clinical and Experimental Rheumatology S.A.S.",
number = "1",

}

TY - JOUR

T1 - Lymphocytic hypophysitis in a patient with systemic lupus erythematosus

AU - Ji, Jong Dae

AU - Lee, S. Y.

AU - Choi, Sungjae

AU - Lee, Young Ho

AU - Song, Gwan Gyu

PY - 2000/2/29

Y1 - 2000/2/29

N2 - A case of lymphocytic hypophysitis in a patient with systemic lupus erythematosus is described. A 20-year-old woman was admitted to our hospital with generalized myalgia and facial rash in May 1998. The patient had a medical history, physical examination, and laboratory findings compatible with systemic lupus erythematosus (SLE). Headache and nausea had developed 3 months previously and worsened over the following months. Hormonal investigation showed hypopituitarism except for prolactin. A magnetic resonance image of the brain showed a mass lesion in the pituitary fossa. A trans-sphenoidal surgical procedure was performed which revealed a dark- yellowish hematoma. Microscopic examination showed diffuse infiltration of lymphocytes and plasma cells with fibrosis in the anterior pituitary. Post- operatively the patient's headaches and nausea resolved. This indicates that lymphocytic hypophysitis may be associated with SLE.

AB - A case of lymphocytic hypophysitis in a patient with systemic lupus erythematosus is described. A 20-year-old woman was admitted to our hospital with generalized myalgia and facial rash in May 1998. The patient had a medical history, physical examination, and laboratory findings compatible with systemic lupus erythematosus (SLE). Headache and nausea had developed 3 months previously and worsened over the following months. Hormonal investigation showed hypopituitarism except for prolactin. A magnetic resonance image of the brain showed a mass lesion in the pituitary fossa. A trans-sphenoidal surgical procedure was performed which revealed a dark- yellowish hematoma. Microscopic examination showed diffuse infiltration of lymphocytes and plasma cells with fibrosis in the anterior pituitary. Post- operatively the patient's headaches and nausea resolved. This indicates that lymphocytic hypophysitis may be associated with SLE.

KW - Lymphocytic hypophysitis

KW - Systemic lupus erythematosus

UR - http://www.scopus.com/inward/record.url?scp=0033967005&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0033967005&partnerID=8YFLogxK

M3 - Article

C2 - 10728449

AN - SCOPUS:0033967005

VL - 18

SP - 78

EP - 80

JO - Clinical and Experimental Rheumatology

JF - Clinical and Experimental Rheumatology

SN - 0392-856X

IS - 1

ER -