Abstract
A case of lymphocytic hypophysitis in a patient with systemic lupus erythematosus is described. A 20-year-old woman was admitted to our hospital with generalized myalgia and facial rash in May 1998. The patient had a medical history, physical examination, and laboratory findings compatible with systemic lupus erythematosus (SLE). Headache and nausea had developed 3 months previously and worsened over the following months. Hormonal investigation showed hypopituitarism except for prolactin. A magnetic resonance image of the brain showed a mass lesion in the pituitary fossa. A trans-sphenoidal surgical procedure was performed which revealed a dark- yellowish hematoma. Microscopic examination showed diffuse infiltration of lymphocytes and plasma cells with fibrosis in the anterior pituitary. Post- operatively the patient's headaches and nausea resolved. This indicates that lymphocytic hypophysitis may be associated with SLE.
| Original language | English |
|---|---|
| Pages (from-to) | 78-80 |
| Number of pages | 3 |
| Journal | Clinical and experimental rheumatology |
| Volume | 18 |
| Issue number | 1 |
| Publication status | Published - 2000 |
| Externally published | Yes |
Keywords
- Lymphocytic hypophysitis
- Systemic lupus erythematosus
ASJC Scopus subject areas
- Immunology and Allergy
- Rheumatology
- Immunology