Abstract
A case of lymphocytic hypophysitis in a patient with systemic lupus erythematosus is described. A 20-year-old woman was admitted to our hospital with generalized myalgia and facial rash in May 1998. The patient had a medical history, physical examination, and laboratory findings compatible with systemic lupus erythematosus (SLE). Headache and nausea had developed 3 months previously and worsened over the following months. Hormonal investigation showed hypopituitarism except for prolactin. A magnetic resonance image of the brain showed a mass lesion in the pituitary fossa. A trans-sphenoidal surgical procedure was performed which revealed a dark- yellowish hematoma. Microscopic examination showed diffuse infiltration of lymphocytes and plasma cells with fibrosis in the anterior pituitary. Post- operatively the patient's headaches and nausea resolved. This indicates that lymphocytic hypophysitis may be associated with SLE.
| Original language | English |
|---|---|
| Pages (from-to) | 78-80 |
| Number of pages | 3 |
| Journal | Clinical and Experimental Rheumatology |
| Volume | 18 |
| Issue number | 1 |
| Publication status | Published - 2000 Feb 29 |
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Keywords
- Lymphocytic hypophysitis
- Systemic lupus erythematosus
ASJC Scopus subject areas
- Rheumatology
- Immunology and Allergy
- Immunology
Cite this
Lymphocytic hypophysitis in a patient with systemic lupus erythematosus. / Ji, Jong Dae; Lee, S. Y.; Choi, Sungjae; Lee, Young Ho; Song, Gwan Gyu.
In: Clinical and Experimental Rheumatology, Vol. 18, No. 1, 29.02.2000, p. 78-80.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Lymphocytic hypophysitis in a patient with systemic lupus erythematosus
AU - Ji, Jong Dae
AU - Lee, S. Y.
AU - Choi, Sungjae
AU - Lee, Young Ho
AU - Song, Gwan Gyu
PY - 2000/2/29
Y1 - 2000/2/29
N2 - A case of lymphocytic hypophysitis in a patient with systemic lupus erythematosus is described. A 20-year-old woman was admitted to our hospital with generalized myalgia and facial rash in May 1998. The patient had a medical history, physical examination, and laboratory findings compatible with systemic lupus erythematosus (SLE). Headache and nausea had developed 3 months previously and worsened over the following months. Hormonal investigation showed hypopituitarism except for prolactin. A magnetic resonance image of the brain showed a mass lesion in the pituitary fossa. A trans-sphenoidal surgical procedure was performed which revealed a dark- yellowish hematoma. Microscopic examination showed diffuse infiltration of lymphocytes and plasma cells with fibrosis in the anterior pituitary. Post- operatively the patient's headaches and nausea resolved. This indicates that lymphocytic hypophysitis may be associated with SLE.
AB - A case of lymphocytic hypophysitis in a patient with systemic lupus erythematosus is described. A 20-year-old woman was admitted to our hospital with generalized myalgia and facial rash in May 1998. The patient had a medical history, physical examination, and laboratory findings compatible with systemic lupus erythematosus (SLE). Headache and nausea had developed 3 months previously and worsened over the following months. Hormonal investigation showed hypopituitarism except for prolactin. A magnetic resonance image of the brain showed a mass lesion in the pituitary fossa. A trans-sphenoidal surgical procedure was performed which revealed a dark- yellowish hematoma. Microscopic examination showed diffuse infiltration of lymphocytes and plasma cells with fibrosis in the anterior pituitary. Post- operatively the patient's headaches and nausea resolved. This indicates that lymphocytic hypophysitis may be associated with SLE.
KW - Lymphocytic hypophysitis
KW - Systemic lupus erythematosus
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UR - http://www.scopus.com/inward/citedby.url?scp=0033967005&partnerID=8YFLogxK
M3 - Article
C2 - 10728449
AN - SCOPUS:0033967005
VL - 18
SP - 78
EP - 80
JO - Clinical and Experimental Rheumatology
JF - Clinical and Experimental Rheumatology
SN - 0392-856X
IS - 1
ER -