Macroamylasemia in a patient with acute appendicitis: A case report

Jun Won Um, Kwang Hee Kim, Min Seung Kang, Jeong Hoon Choe, Jeoung Won Bae, Yun Sik Hong, Sung Ock Suh, Young Chul Kim, Cheung Wung Whang, Sae Min Kim

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7 Citations (Scopus)


Macroamylasemia is a condition of persistent, elevated serum amylase activity with no apparent clinical symptoms of a pancreatic disorder. In Korea, however, no such case has been reported to date. We report a case of a 17-year-old female diagnosed with macroamylasemia and acute appendicitis. One day earlier, she developed epigastric and right lower quadrant abdominal pain. She was characterized by high level of serum amylase, but normal lipase. Amylase isoenzyme analysis demonstrated increased fraction of salivary type and follow-up amylase level was persistently increased. Immunofixation disclosed the macroamylase binding with an immunoglobulin, consisting of IgA and kappa chain. The patient was treated by appendectomy, and the abdominal pain subsided.

Original languageEnglish
Pages (from-to)679-681
Number of pages3
JournalJournal of Korean medical science
Issue number6
Publication statusPublished - 1999 Dec


  • Amylases
  • Appendicitis

ASJC Scopus subject areas

  • Medicine(all)

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    Um, J. W., Kim, K. H., Kang, M. S., Choe, J. H., Bae, J. W., Hong, Y. S., Suh, S. O., Kim, Y. C., Whang, C. W., & Kim, S. M. (1999). Macroamylasemia in a patient with acute appendicitis: A case report. Journal of Korean medical science, 14(6), 679-681.