Macrochanneled poly (ε-caprolactone)/hydroxyapatite scaffold by combination of bi-axial machining and lamination

Young Hag Koh, Chang Jun Bae, Jong Jae Sun, In Kook Jun, Hyoun Ee Kim

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

A combination of bi-axial machining and lamination was used to fabricate macrochanneled poly (ε-caprolactone) (PCL)/hydroxyapatite (HA) scaffolds. Thermoplastic PCL/HA sheets with a thickness of 1 mm, consisting of a 40 wt% PCL polymer and 60 wt% HA particles, were bi-axially machined. The thermoplastic PCL/HA exhibited an excellent surface finish with negligible tearing of the PCL polymer and pull-out of the HA particles. The bi-axially machined sheets were laminated with a solvent to give permanent bonding between the lamina. This novel process produced three-directionally connected macrochannels in the dense PCL/HA body. The macrochanneled PCL/HA scaffold exhibited excellent ductility and reasonably high strength. In addition, good cellular responses were observed due to the osteoconductive HA particles.

Original languageEnglish
Pages (from-to)773-778
Number of pages6
JournalJournal of Materials Science: Materials in Medicine
Volume17
Issue number9
DOIs
Publication statusPublished - 2006 Sep

ASJC Scopus subject areas

  • Biophysics
  • Bioengineering
  • Biomaterials
  • Biomedical Engineering

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