Travma hastalarında makrofaj migrasyonunu inhibe edici faktör düzeyleri enfeksiyonla koreledir

Translated title of the contribution: Macrophage migration inhibitory factor levels correlate with an infection in trauma patients

Research output: Contribution to journalArticle

Abstract

BACKGROUND: The role of migration inhibitory factor (MIF) is best understood in septic shock and septic disease; however, the role of MIF in a secondary infection after trauma has not yet been completely studied. This study aimed to evaluate the role of MIF in trauma patients. METHODS: The patients in the study population were divided into two groups according to the results of their MIF levels. The initial MIF levels, trauma mechanism, revised trauma score, survival rate, length of stay (LOS) in the intensive care unit (ICU), level of leukocytes, and level of C-reactive protein (CRP) were compared between the groups. RESULTS: Overall, 116 patients were enrolled from August 1, 2014 to July 31, 2015. LOS in ICU in the elevated MIF group was 5.67±7.54 days compared with 2.09±2.26 days in the normal MIF group. Further, CRP level in the elevated MIF group was higher than that in the normal MIF group. CONCLUSION: In a place such as the department of emergency medicine, it is critical and important for emergency physicians to make a proper judgment and to prepare for the worst scenario. Therefore, the utilization of MIF level in trauma patients has a possibility for assisting emergency physicians.

Original languageTurkish
Pages (from-to)193-198
Number of pages6
JournalUlusal Travma ve Acil Cerrahi Dergisi
Volume23
Issue number3
DOIs
Publication statusPublished - 2017 May 1

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Macrophage Migration-Inhibitory Factors
Wounds and Injuries
Infection
C-Reactive Protein
Intensive Care Units
Length of Stay
Emergencies
Physicians
Emergency Medicine
Septic Shock
Coinfection
Leukocytes
Survival Rate
Population

Keywords

  • Infection
  • Macrophage migration inhibitory factor
  • Trauma

ASJC Scopus subject areas

  • Surgery
  • Emergency Medicine
  • Anesthesiology and Pain Medicine

Cite this

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title = "Travma hastalarında makrofaj migrasyonunu inhibe edici fakt{\"o}r d{\"u}zeyleri enfeksiyonla koreledir",
abstract = "BACKGROUND: The role of migration inhibitory factor (MIF) is best understood in septic shock and septic disease; however, the role of MIF in a secondary infection after trauma has not yet been completely studied. This study aimed to evaluate the role of MIF in trauma patients. METHODS: The patients in the study population were divided into two groups according to the results of their MIF levels. The initial MIF levels, trauma mechanism, revised trauma score, survival rate, length of stay (LOS) in the intensive care unit (ICU), level of leukocytes, and level of C-reactive protein (CRP) were compared between the groups. RESULTS: Overall, 116 patients were enrolled from August 1, 2014 to July 31, 2015. LOS in ICU in the elevated MIF group was 5.67±7.54 days compared with 2.09±2.26 days in the normal MIF group. Further, CRP level in the elevated MIF group was higher than that in the normal MIF group. CONCLUSION: In a place such as the department of emergency medicine, it is critical and important for emergency physicians to make a proper judgment and to prepare for the worst scenario. Therefore, the utilization of MIF level in trauma patients has a possibility for assisting emergency physicians.",
keywords = "Infection, Macrophage migration inhibitory factor, Trauma",
author = "Cho, {Young Duck} and Choi, {Sung Hyuk} and Jung-Youn Kim and Park, {Sung Jun} and Young-Hoon Yoon and Cho, {Han Jin} and Yeom, {Ji Won}",
year = "2017",
month = "5",
day = "1",
doi = "10.5505/tjtes.2016.04780",
language = "Turkish",
volume = "23",
pages = "193--198",
journal = "Ulusal Travma ve Acil Cerrahi Dergisi",
issn = "1306-696X",
publisher = "Turkish Association of Trauma and Emergency Surgery",
number = "3",

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T1 - Travma hastalarında makrofaj migrasyonunu inhibe edici faktör düzeyleri enfeksiyonla koreledir

AU - Cho, Young Duck

AU - Choi, Sung Hyuk

AU - Kim, Jung-Youn

AU - Park, Sung Jun

AU - Yoon, Young-Hoon

AU - Cho, Han Jin

AU - Yeom, Ji Won

PY - 2017/5/1

Y1 - 2017/5/1

N2 - BACKGROUND: The role of migration inhibitory factor (MIF) is best understood in septic shock and septic disease; however, the role of MIF in a secondary infection after trauma has not yet been completely studied. This study aimed to evaluate the role of MIF in trauma patients. METHODS: The patients in the study population were divided into two groups according to the results of their MIF levels. The initial MIF levels, trauma mechanism, revised trauma score, survival rate, length of stay (LOS) in the intensive care unit (ICU), level of leukocytes, and level of C-reactive protein (CRP) were compared between the groups. RESULTS: Overall, 116 patients were enrolled from August 1, 2014 to July 31, 2015. LOS in ICU in the elevated MIF group was 5.67±7.54 days compared with 2.09±2.26 days in the normal MIF group. Further, CRP level in the elevated MIF group was higher than that in the normal MIF group. CONCLUSION: In a place such as the department of emergency medicine, it is critical and important for emergency physicians to make a proper judgment and to prepare for the worst scenario. Therefore, the utilization of MIF level in trauma patients has a possibility for assisting emergency physicians.

AB - BACKGROUND: The role of migration inhibitory factor (MIF) is best understood in septic shock and septic disease; however, the role of MIF in a secondary infection after trauma has not yet been completely studied. This study aimed to evaluate the role of MIF in trauma patients. METHODS: The patients in the study population were divided into two groups according to the results of their MIF levels. The initial MIF levels, trauma mechanism, revised trauma score, survival rate, length of stay (LOS) in the intensive care unit (ICU), level of leukocytes, and level of C-reactive protein (CRP) were compared between the groups. RESULTS: Overall, 116 patients were enrolled from August 1, 2014 to July 31, 2015. LOS in ICU in the elevated MIF group was 5.67±7.54 days compared with 2.09±2.26 days in the normal MIF group. Further, CRP level in the elevated MIF group was higher than that in the normal MIF group. CONCLUSION: In a place such as the department of emergency medicine, it is critical and important for emergency physicians to make a proper judgment and to prepare for the worst scenario. Therefore, the utilization of MIF level in trauma patients has a possibility for assisting emergency physicians.

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