Abstract
Magnetic nanoparticles offer potential advances in cancer treatment. One example is cancer theranostics, which refers to the combination of a diagnostic tool, i.e., magnetic resonance (MR) imaging, and therapeutic entities such as drugs, oligonucleotides, antibodies, and peptides. They can be conjugated with bioactive molecules and have the ability to form a magnetic field gradient under an external magnetic field. They can offer a variety of active drug delivery and imaging strategies along with modalities such as magnetic hyperthermia. Imaging with magnetic nanoparticles can facilitate more effective cancer therapy through more well informed decision-making. In this article, we review notable progress in magnetic particle design, including surface modifications and multi-functionalization, and we discuss the recent bioapplications of magnetic nanoparticles in simultaneous cancer imaging and therapy.
| Original language | English |
|---|---|
| Pages (from-to) | 729-739 |
| Number of pages | 11 |
| Journal | Journal of Materials Chemistry B |
| Volume | 1 |
| Issue number | 6 |
| DOIs | |
| Publication status | Published - 2013 Feb 14 |
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ASJC Scopus subject areas
- Chemistry(all)
- Biomedical Engineering
- Medicine(all)
- Materials Science(all)
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Magnetic nanocomplexes and the physiological challenges associated with their use for cancer imaging and therapy. / Kim, Eunjung; Lee, Kwangyeol; Huh, Yong Min; Haam, Seungjoo.
In: Journal of Materials Chemistry B, Vol. 1, No. 6, 14.02.2013, p. 729-739.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Magnetic nanocomplexes and the physiological challenges associated with their use for cancer imaging and therapy
AU - Kim, Eunjung
AU - Lee, Kwangyeol
AU - Huh, Yong Min
AU - Haam, Seungjoo
PY - 2013/2/14
Y1 - 2013/2/14
N2 - Magnetic nanoparticles offer potential advances in cancer treatment. One example is cancer theranostics, which refers to the combination of a diagnostic tool, i.e., magnetic resonance (MR) imaging, and therapeutic entities such as drugs, oligonucleotides, antibodies, and peptides. They can be conjugated with bioactive molecules and have the ability to form a magnetic field gradient under an external magnetic field. They can offer a variety of active drug delivery and imaging strategies along with modalities such as magnetic hyperthermia. Imaging with magnetic nanoparticles can facilitate more effective cancer therapy through more well informed decision-making. In this article, we review notable progress in magnetic particle design, including surface modifications and multi-functionalization, and we discuss the recent bioapplications of magnetic nanoparticles in simultaneous cancer imaging and therapy.
AB - Magnetic nanoparticles offer potential advances in cancer treatment. One example is cancer theranostics, which refers to the combination of a diagnostic tool, i.e., magnetic resonance (MR) imaging, and therapeutic entities such as drugs, oligonucleotides, antibodies, and peptides. They can be conjugated with bioactive molecules and have the ability to form a magnetic field gradient under an external magnetic field. They can offer a variety of active drug delivery and imaging strategies along with modalities such as magnetic hyperthermia. Imaging with magnetic nanoparticles can facilitate more effective cancer therapy through more well informed decision-making. In this article, we review notable progress in magnetic particle design, including surface modifications and multi-functionalization, and we discuss the recent bioapplications of magnetic nanoparticles in simultaneous cancer imaging and therapy.
UR - http://www.scopus.com/inward/record.url?scp=84876532388&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84876532388&partnerID=8YFLogxK
U2 - 10.1039/c2tb00294a
DO - 10.1039/c2tb00294a
M3 - Article
AN - SCOPUS:84876532388
VL - 1
SP - 729
EP - 739
JO - Journal of Materials Chemistry B
JF - Journal of Materials Chemistry B
SN - 2050-7518
IS - 6
ER -