TY - JOUR
T1 - Magnetic Particle Spectrometry of Fe3O4 Multi-Granule Nanoclusters
AU - Pan, Lijun
AU - Park, Bum Chul
AU - Ledwig, Micheal
AU - Abelmann, Leon
AU - Kim, Young Keun
N1 - Funding Information:
ACKNOWLEDGMENT This research was supported by the National Research Foundation of Korea under Grant 2014M3A7B4052193 and Grant 2015R1A2A1A15053002.
PY - 2017/11
Y1 - 2017/11
N2 - Magnetic particle imaging (MPI) is a novel high-resolution medical imaging method that does not use ionizing radiation, but safe iron oxide nanoparticles as contrast agents. By employing magnetite (Fe3O4) multi-granule nanoclusters (MGNCs), one has two control parameters: the diameter of the particles and that of granules in single particles. Here we investigate the effect of the size of the particles at constant granule size, as well as the effect of granule size at constant particle size on the magnetization reversal. The saturation magnetization Ms value increases with increasing granule diameter and particle diameter, while the coercivity Hc value reaches a maximum at a particle size of about 60 nm. MGNCs with an average particle size of 77 nm and granule diameter of 17 nm show a larger response in the higher harmonics compared to the commercial reference, FeraSpin R dispersion, at both 20 and 30 mT. This result demonstrates that the MGNC concept allows tailoring of the magnetic properties of the particles to the imaging conditions in MPI.
AB - Magnetic particle imaging (MPI) is a novel high-resolution medical imaging method that does not use ionizing radiation, but safe iron oxide nanoparticles as contrast agents. By employing magnetite (Fe3O4) multi-granule nanoclusters (MGNCs), one has two control parameters: the diameter of the particles and that of granules in single particles. Here we investigate the effect of the size of the particles at constant granule size, as well as the effect of granule size at constant particle size on the magnetization reversal. The saturation magnetization Ms value increases with increasing granule diameter and particle diameter, while the coercivity Hc value reaches a maximum at a particle size of about 60 nm. MGNCs with an average particle size of 77 nm and granule diameter of 17 nm show a larger response in the higher harmonics compared to the commercial reference, FeraSpin R dispersion, at both 20 and 30 mT. This result demonstrates that the MGNC concept allows tailoring of the magnetic properties of the particles to the imaging conditions in MPI.
KW - FeO
KW - magnetic particle spectrometry
KW - magnetic properties
KW - multi-granule nanoclusters (MGNCs)
UR - http://www.scopus.com/inward/record.url?scp=85032955585&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85032955585&partnerID=8YFLogxK
U2 - 10.1109/TMAG.2017.2701904
DO - 10.1109/TMAG.2017.2701904
M3 - Article
AN - SCOPUS:85032955585
VL - 53
JO - IEEE Transactions on Magnetics
JF - IEEE Transactions on Magnetics
SN - 0018-9464
IS - 11
M1 - 7921601
ER -