Magnetic sensitivity enhanced novel fluorescent magnetic silica nanoparticles for biomedical applications

Jaemoon Yang, Jaewon Lee, Jinyoung Kang, Chan Hwa Chung, Kwangyeol Lee, Jin Suck Suh, Ho Geun Yoon, Yong Min Huh, Seungjoo Haam

Research output: Contribution to journalArticle

22 Citations (Scopus)

Abstract

We synthesized novel fluorescent magnetic silica nanoparticles (FMSNPs) containing large magnetic components for biomedical application. By employing assemblies of magnetic nanoparticles as kernels against FMSNPs, both the saturation of magnetization and the magnetic resonance (MR) signal intensity were significantly enhanced. Furthermore, the cellular binding of FMSNPs was improved by introducing a positive charge on the surface of the FMSNPs, and fluorescent dyes on the surface of FMSNPs enable optical imaging of sub-cellular regions.

Original languageEnglish
Article number075610
JournalNanotechnology
Volume19
Issue number7
DOIs
Publication statusPublished - 2008 Feb 14

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Silicon Dioxide
Nanoparticles
Silica
Optical Imaging
Magnetic resonance
Fluorescent Dyes
Magnetization
Magnetic Resonance Spectroscopy
Dyes
Imaging techniques

ASJC Scopus subject areas

  • Materials Science(all)
  • Bioengineering
  • Chemistry(all)
  • Electrical and Electronic Engineering
  • Mechanical Engineering
  • Mechanics of Materials

Cite this

Magnetic sensitivity enhanced novel fluorescent magnetic silica nanoparticles for biomedical applications. / Yang, Jaemoon; Lee, Jaewon; Kang, Jinyoung; Chung, Chan Hwa; Lee, Kwangyeol; Suh, Jin Suck; Yoon, Ho Geun; Huh, Yong Min; Haam, Seungjoo.

In: Nanotechnology, Vol. 19, No. 7, 075610, 14.02.2008.

Research output: Contribution to journalArticle

Yang, Jaemoon ; Lee, Jaewon ; Kang, Jinyoung ; Chung, Chan Hwa ; Lee, Kwangyeol ; Suh, Jin Suck ; Yoon, Ho Geun ; Huh, Yong Min ; Haam, Seungjoo. / Magnetic sensitivity enhanced novel fluorescent magnetic silica nanoparticles for biomedical applications. In: Nanotechnology. 2008 ; Vol. 19, No. 7.
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