Magnetically driven spinning nanowires as effective materials for eradicating living cells

Daniel S. Choi, Xiaoping Hopkins, Rosemarie Kringel, Jungrae Park, In Tak Jeon, Young-geun Kim

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

We present a method to inflame cells, in vitro, by applying an alternating current (ac) magnetic field to ferromagnetic nanowires (NWs) internalized by living cells. Nickel (Ni) NWs were internalized by human embryonic kidney cells (HEK-293). The application of ac magnetic field to the cells induced spinning of the cells via the motion of internalized NWs. This resulted in cell death by physically causing damage. A study of the response of cytokine to cells with spinning NWs shows increased interleukin-6 effects when compared with responses from non-spinning cells. The spinning effect of cells caused by the application of magnetic field can be used to target and inflame the cells. Such experiments suggest the possibility of inflaming cells for the treatment of cancer.

Original languageEnglish
Article number07B329
JournalJournal of Applied Physics
Volume111
Issue number7
DOIs
Publication statusPublished - 2012 Apr 1

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metal spinning
nanowires
cells
alternating current
magnetic fields
interleukins
kidneys
death
cancer
nickel
damage

ASJC Scopus subject areas

  • Physics and Astronomy(all)

Cite this

Magnetically driven spinning nanowires as effective materials for eradicating living cells. / Choi, Daniel S.; Hopkins, Xiaoping; Kringel, Rosemarie; Park, Jungrae; Jeon, In Tak; Kim, Young-geun.

In: Journal of Applied Physics, Vol. 111, No. 7, 07B329, 01.04.2012.

Research output: Contribution to journalArticle

Choi, Daniel S. ; Hopkins, Xiaoping ; Kringel, Rosemarie ; Park, Jungrae ; Jeon, In Tak ; Kim, Young-geun. / Magnetically driven spinning nanowires as effective materials for eradicating living cells. In: Journal of Applied Physics. 2012 ; Vol. 111, No. 7.
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