Abstract
Neonatal maple syrup urine disease (MSUD) is associated with diffuse oedema and characteristic MSUD oedema. We present a newborn infant with two coexisting different types of oedema. The myelinated white matter showed a marked decrease in the water apparent diffusion coefficient (ADC) compatible with cytotoxic oedema. The unmyelinated white matter showed an increase in ADC, consistent with vasogenic-interstitial oedema. On follow-up studies, the cytotoxic oedema showed improvement, but the vasogenic-interstitial oedema progressed into brain atrophy.
| Original language | English |
|---|---|
| Pages (from-to) | 163-166 |
| Number of pages | 4 |
| Journal | Pediatric Radiology |
| Volume | 34 |
| Issue number | 2 |
| DOIs | |
| Publication status | Published - 2004 Feb 1 |
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Keywords
- Brain
- Diffusion-weighted MRI
- Maple syrup urine disease
- Metabolic
- Neonate
ASJC Scopus subject areas
- Radiology Nuclear Medicine and imaging
- Pediatrics, Perinatology, and Child Health
- Radiological and Ultrasound Technology
Cite this
Maple syrup urine disease encephalopathy : A follow-up study in the acute stage using diffusion-weighted MRI. / Ha, Jong Su; Kim, Taik Kun; Eun, Baik-Lin; Lee, Hee Sun; Lee, Ki Yeol; Seol, Hae Young; Cha, Sang Hoon.
In: Pediatric Radiology, Vol. 34, No. 2, 01.02.2004, p. 163-166.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Maple syrup urine disease encephalopathy
T2 - A follow-up study in the acute stage using diffusion-weighted MRI
AU - Ha, Jong Su
AU - Kim, Taik Kun
AU - Eun, Baik-Lin
AU - Lee, Hee Sun
AU - Lee, Ki Yeol
AU - Seol, Hae Young
AU - Cha, Sang Hoon
PY - 2004/2/1
Y1 - 2004/2/1
N2 - Neonatal maple syrup urine disease (MSUD) is associated with diffuse oedema and characteristic MSUD oedema. We present a newborn infant with two coexisting different types of oedema. The myelinated white matter showed a marked decrease in the water apparent diffusion coefficient (ADC) compatible with cytotoxic oedema. The unmyelinated white matter showed an increase in ADC, consistent with vasogenic-interstitial oedema. On follow-up studies, the cytotoxic oedema showed improvement, but the vasogenic-interstitial oedema progressed into brain atrophy.
AB - Neonatal maple syrup urine disease (MSUD) is associated with diffuse oedema and characteristic MSUD oedema. We present a newborn infant with two coexisting different types of oedema. The myelinated white matter showed a marked decrease in the water apparent diffusion coefficient (ADC) compatible with cytotoxic oedema. The unmyelinated white matter showed an increase in ADC, consistent with vasogenic-interstitial oedema. On follow-up studies, the cytotoxic oedema showed improvement, but the vasogenic-interstitial oedema progressed into brain atrophy.
KW - Brain
KW - Diffusion-weighted MRI
KW - Maple syrup urine disease
KW - Metabolic
KW - Neonate
UR - http://www.scopus.com/inward/record.url?scp=1042291995&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=1042291995&partnerID=8YFLogxK
U2 - 10.1007/s00247-003-1058-7
DO - 10.1007/s00247-003-1058-7
M3 - Article
C2 - 14504844
AN - SCOPUS:1042291995
VL - 34
SP - 163
EP - 166
JO - Pediatric Radiology
JF - Pediatric Radiology
SN - 0301-0449
IS - 2
ER -