Abstract
Neonatal maple syrup urine disease (MSUD) is associated with diffuse oedema and characteristic MSUD oedema. We present a newborn infant with two coexisting different types of oedema. The myelinated white matter showed a marked decrease in the water apparent diffusion coefficient (ADC) compatible with cytotoxic oedema. The unmyelinated white matter showed an increase in ADC, consistent with vasogenic-interstitial oedema. On follow-up studies, the cytotoxic oedema showed improvement, but the vasogenic-interstitial oedema progressed into brain atrophy.
Original language | English |
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Pages (from-to) | 163-166 |
Number of pages | 4 |
Journal | Pediatric Radiology |
Volume | 34 |
Issue number | 2 |
DOIs | |
Publication status | Published - 2004 Feb |
Keywords
- Brain
- Diffusion-weighted MRI
- Maple syrup urine disease
- Metabolic
- Neonate
ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health
- Radiology Nuclear Medicine and imaging