Measurement of blood viscosity using a pressure-scanning capillary viscometer

Sehyun Shin, Yunhee Ku, Myung Su Park, Jang Soo Suh

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

A newly designed pressure-scanning capillary viscometer is extended to measure the viscosity of whole blood over a range of shear rates without the use of anticoagulants in a clinical setting. In the present study, a single measurement of pressure variation with time replaces the flow rate and pressure drop measurements that are usually required for the operation of a capillary tube viscometer. Using a pressure transducer and capillary, we measured the variation of pressure flowing through capillary tube with respect to time, p(t), from which viscosity and the shear rate were mathematically calculated. For water and anticoagulant-added bloods, there was an excellent agreement found between the results from the pressure scanning capillary viscometer and those from a commercially available rotating viscometer. Also, the pressure-scanning capillary viscometer measured the viscosity of whole blood without heparin or EDTA. This new method overcomes the drawbacks of conventional viscometers in the measurement of whole blood viscosity. First, the pressure-scanning capillary viscometer can accurately and consistently measure the whole blood viscosity over a range of shear rates in less than 2 min without any anticoagulants. Second, this design provides simplicity (i.e., ease of operation, no moving parts, and disposable) and low cost.

Original languageEnglish
Pages (from-to)467-470
Number of pages4
JournalClinical Hemorheology and Microcirculation
Volume30
Issue number3-4
Publication statusPublished - 2004 Aug 2
Externally publishedYes

Fingerprint

Blood Viscosity
Pressure
Anticoagulants
Pressure Transducers
Viscosity
Edetic Acid
Heparin
Costs and Cost Analysis
Water

Keywords

  • Blood
  • Capillary viscometer
  • Pressure
  • Shear rate
  • Viscosity

ASJC Scopus subject areas

  • Hematology
  • Physiology

Cite this

Measurement of blood viscosity using a pressure-scanning capillary viscometer. / Shin, Sehyun; Ku, Yunhee; Park, Myung Su; Suh, Jang Soo.

In: Clinical Hemorheology and Microcirculation, Vol. 30, No. 3-4, 02.08.2004, p. 467-470.

Research output: Contribution to journalArticle

Shin, Sehyun ; Ku, Yunhee ; Park, Myung Su ; Suh, Jang Soo. / Measurement of blood viscosity using a pressure-scanning capillary viscometer. In: Clinical Hemorheology and Microcirculation. 2004 ; Vol. 30, No. 3-4. pp. 467-470.
@article{8080bc7ed77540058c90f27eb85a2988,
title = "Measurement of blood viscosity using a pressure-scanning capillary viscometer",
abstract = "A newly designed pressure-scanning capillary viscometer is extended to measure the viscosity of whole blood over a range of shear rates without the use of anticoagulants in a clinical setting. In the present study, a single measurement of pressure variation with time replaces the flow rate and pressure drop measurements that are usually required for the operation of a capillary tube viscometer. Using a pressure transducer and capillary, we measured the variation of pressure flowing through capillary tube with respect to time, p(t), from which viscosity and the shear rate were mathematically calculated. For water and anticoagulant-added bloods, there was an excellent agreement found between the results from the pressure scanning capillary viscometer and those from a commercially available rotating viscometer. Also, the pressure-scanning capillary viscometer measured the viscosity of whole blood without heparin or EDTA. This new method overcomes the drawbacks of conventional viscometers in the measurement of whole blood viscosity. First, the pressure-scanning capillary viscometer can accurately and consistently measure the whole blood viscosity over a range of shear rates in less than 2 min without any anticoagulants. Second, this design provides simplicity (i.e., ease of operation, no moving parts, and disposable) and low cost.",
keywords = "Blood, Capillary viscometer, Pressure, Shear rate, Viscosity",
author = "Sehyun Shin and Yunhee Ku and Park, {Myung Su} and Suh, {Jang Soo}",
year = "2004",
month = "8",
day = "2",
language = "English",
volume = "30",
pages = "467--470",
journal = "Clinical Hemorheology and Microcirculation",
issn = "1386-0291",
publisher = "IOS Press",
number = "3-4",

}

TY - JOUR

T1 - Measurement of blood viscosity using a pressure-scanning capillary viscometer

AU - Shin, Sehyun

AU - Ku, Yunhee

AU - Park, Myung Su

AU - Suh, Jang Soo

PY - 2004/8/2

Y1 - 2004/8/2

N2 - A newly designed pressure-scanning capillary viscometer is extended to measure the viscosity of whole blood over a range of shear rates without the use of anticoagulants in a clinical setting. In the present study, a single measurement of pressure variation with time replaces the flow rate and pressure drop measurements that are usually required for the operation of a capillary tube viscometer. Using a pressure transducer and capillary, we measured the variation of pressure flowing through capillary tube with respect to time, p(t), from which viscosity and the shear rate were mathematically calculated. For water and anticoagulant-added bloods, there was an excellent agreement found between the results from the pressure scanning capillary viscometer and those from a commercially available rotating viscometer. Also, the pressure-scanning capillary viscometer measured the viscosity of whole blood without heparin or EDTA. This new method overcomes the drawbacks of conventional viscometers in the measurement of whole blood viscosity. First, the pressure-scanning capillary viscometer can accurately and consistently measure the whole blood viscosity over a range of shear rates in less than 2 min without any anticoagulants. Second, this design provides simplicity (i.e., ease of operation, no moving parts, and disposable) and low cost.

AB - A newly designed pressure-scanning capillary viscometer is extended to measure the viscosity of whole blood over a range of shear rates without the use of anticoagulants in a clinical setting. In the present study, a single measurement of pressure variation with time replaces the flow rate and pressure drop measurements that are usually required for the operation of a capillary tube viscometer. Using a pressure transducer and capillary, we measured the variation of pressure flowing through capillary tube with respect to time, p(t), from which viscosity and the shear rate were mathematically calculated. For water and anticoagulant-added bloods, there was an excellent agreement found between the results from the pressure scanning capillary viscometer and those from a commercially available rotating viscometer. Also, the pressure-scanning capillary viscometer measured the viscosity of whole blood without heparin or EDTA. This new method overcomes the drawbacks of conventional viscometers in the measurement of whole blood viscosity. First, the pressure-scanning capillary viscometer can accurately and consistently measure the whole blood viscosity over a range of shear rates in less than 2 min without any anticoagulants. Second, this design provides simplicity (i.e., ease of operation, no moving parts, and disposable) and low cost.

KW - Blood

KW - Capillary viscometer

KW - Pressure

KW - Shear rate

KW - Viscosity

UR - http://www.scopus.com/inward/record.url?scp=3242659785&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=3242659785&partnerID=8YFLogxK

M3 - Article

C2 - 15258389

AN - SCOPUS:3242659785

VL - 30

SP - 467

EP - 470

JO - Clinical Hemorheology and Microcirculation

JF - Clinical Hemorheology and Microcirculation

SN - 1386-0291

IS - 3-4

ER -