Measuring longitudinally dynamic cortex development in infants by reconstruction of consistent cortical surfaces

Gang Li, Jingxin Nie, Li Wang, Feng Shi, John H. Gilmore, Weili Lin, Dinggang Shen

Research output: Chapter in Book/Report/Conference proceedingConference contribution

3 Citations (Scopus)

Abstract

Quantitative measurement of dynamic cortex development during early postnatal stages is of great importance to understand early cortical structural and functional development. Conventional methods usually independently reconstruct cortical surfaces of longitudinal images from the same infant, which often generates longitudinally-inconsistent cortical surfaces and leads to inconsistence in cortex development measurement. This paper aims to address this problem by presenting a method to reconstruct consistent cortical surfaces from longitudinal brain MR images in the first-year infants for accurate and consistent measurement of dynamic cortex development. Specifically, longitudinal development of the inner cortical surface is first modeled by a deformable sheet with elasto-plasticity property to establish longitudinally smooth correspondences of inner cortical surfaces. Then, the modeled longitudinal inner cortical surfaces are jointly deformed to locate inner and outer cortical surfaces with a spatial-temporal deformable surface. The method has been applied on 10 infants, each with 5 or 6 scans acquired at every 3 months from birth. Experimental results show that our method can accurately and consistently reconstruct dynamic cortical surfaces from longitudinal infant images, with the average surface distance as low as 0.2mm. By using our method, we can quantitatively characterize longitudinally dynamic cortical thickness development in the first-year infants.

Original languageEnglish
Title of host publicationProceedings - International Symposium on Biomedical Imaging
Pages1380-1383
Number of pages4
DOIs
Publication statusPublished - 2013 Aug 22
Externally publishedYes
Event2013 IEEE 10th International Symposium on Biomedical Imaging: From Nano to Macro, ISBI 2013 - San Francisco, CA, United States
Duration: 2013 Apr 72013 Apr 11

Other

Other2013 IEEE 10th International Symposium on Biomedical Imaging: From Nano to Macro, ISBI 2013
CountryUnited States
CitySan Francisco, CA
Period13/4/713/4/11

Fingerprint

Child Development
Parturition
Brain
Plasticity

Keywords

  • infant cortical thickness development
  • infant longitudinal cortical surfaces

ASJC Scopus subject areas

  • Biomedical Engineering
  • Radiology Nuclear Medicine and imaging

Cite this

Li, G., Nie, J., Wang, L., Shi, F., Gilmore, J. H., Lin, W., & Shen, D. (2013). Measuring longitudinally dynamic cortex development in infants by reconstruction of consistent cortical surfaces. In Proceedings - International Symposium on Biomedical Imaging (pp. 1380-1383). [6556790] https://doi.org/10.1109/ISBI.2013.6556790

Measuring longitudinally dynamic cortex development in infants by reconstruction of consistent cortical surfaces. / Li, Gang; Nie, Jingxin; Wang, Li; Shi, Feng; Gilmore, John H.; Lin, Weili; Shen, Dinggang.

Proceedings - International Symposium on Biomedical Imaging. 2013. p. 1380-1383 6556790.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Li, G, Nie, J, Wang, L, Shi, F, Gilmore, JH, Lin, W & Shen, D 2013, Measuring longitudinally dynamic cortex development in infants by reconstruction of consistent cortical surfaces. in Proceedings - International Symposium on Biomedical Imaging., 6556790, pp. 1380-1383, 2013 IEEE 10th International Symposium on Biomedical Imaging: From Nano to Macro, ISBI 2013, San Francisco, CA, United States, 13/4/7. https://doi.org/10.1109/ISBI.2013.6556790
Li G, Nie J, Wang L, Shi F, Gilmore JH, Lin W et al. Measuring longitudinally dynamic cortex development in infants by reconstruction of consistent cortical surfaces. In Proceedings - International Symposium on Biomedical Imaging. 2013. p. 1380-1383. 6556790 https://doi.org/10.1109/ISBI.2013.6556790
Li, Gang ; Nie, Jingxin ; Wang, Li ; Shi, Feng ; Gilmore, John H. ; Lin, Weili ; Shen, Dinggang. / Measuring longitudinally dynamic cortex development in infants by reconstruction of consistent cortical surfaces. Proceedings - International Symposium on Biomedical Imaging. 2013. pp. 1380-1383
@inproceedings{48b3a508fae3469d8955793772fa91d0,
title = "Measuring longitudinally dynamic cortex development in infants by reconstruction of consistent cortical surfaces",
abstract = "Quantitative measurement of dynamic cortex development during early postnatal stages is of great importance to understand early cortical structural and functional development. Conventional methods usually independently reconstruct cortical surfaces of longitudinal images from the same infant, which often generates longitudinally-inconsistent cortical surfaces and leads to inconsistence in cortex development measurement. This paper aims to address this problem by presenting a method to reconstruct consistent cortical surfaces from longitudinal brain MR images in the first-year infants for accurate and consistent measurement of dynamic cortex development. Specifically, longitudinal development of the inner cortical surface is first modeled by a deformable sheet with elasto-plasticity property to establish longitudinally smooth correspondences of inner cortical surfaces. Then, the modeled longitudinal inner cortical surfaces are jointly deformed to locate inner and outer cortical surfaces with a spatial-temporal deformable surface. The method has been applied on 10 infants, each with 5 or 6 scans acquired at every 3 months from birth. Experimental results show that our method can accurately and consistently reconstruct dynamic cortical surfaces from longitudinal infant images, with the average surface distance as low as 0.2mm. By using our method, we can quantitatively characterize longitudinally dynamic cortical thickness development in the first-year infants.",
keywords = "infant cortical thickness development, infant longitudinal cortical surfaces",
author = "Gang Li and Jingxin Nie and Li Wang and Feng Shi and Gilmore, {John H.} and Weili Lin and Dinggang Shen",
year = "2013",
month = "8",
day = "22",
doi = "10.1109/ISBI.2013.6556790",
language = "English",
isbn = "9781467364546",
pages = "1380--1383",
booktitle = "Proceedings - International Symposium on Biomedical Imaging",

}

TY - GEN

T1 - Measuring longitudinally dynamic cortex development in infants by reconstruction of consistent cortical surfaces

AU - Li, Gang

AU - Nie, Jingxin

AU - Wang, Li

AU - Shi, Feng

AU - Gilmore, John H.

AU - Lin, Weili

AU - Shen, Dinggang

PY - 2013/8/22

Y1 - 2013/8/22

N2 - Quantitative measurement of dynamic cortex development during early postnatal stages is of great importance to understand early cortical structural and functional development. Conventional methods usually independently reconstruct cortical surfaces of longitudinal images from the same infant, which often generates longitudinally-inconsistent cortical surfaces and leads to inconsistence in cortex development measurement. This paper aims to address this problem by presenting a method to reconstruct consistent cortical surfaces from longitudinal brain MR images in the first-year infants for accurate and consistent measurement of dynamic cortex development. Specifically, longitudinal development of the inner cortical surface is first modeled by a deformable sheet with elasto-plasticity property to establish longitudinally smooth correspondences of inner cortical surfaces. Then, the modeled longitudinal inner cortical surfaces are jointly deformed to locate inner and outer cortical surfaces with a spatial-temporal deformable surface. The method has been applied on 10 infants, each with 5 or 6 scans acquired at every 3 months from birth. Experimental results show that our method can accurately and consistently reconstruct dynamic cortical surfaces from longitudinal infant images, with the average surface distance as low as 0.2mm. By using our method, we can quantitatively characterize longitudinally dynamic cortical thickness development in the first-year infants.

AB - Quantitative measurement of dynamic cortex development during early postnatal stages is of great importance to understand early cortical structural and functional development. Conventional methods usually independently reconstruct cortical surfaces of longitudinal images from the same infant, which often generates longitudinally-inconsistent cortical surfaces and leads to inconsistence in cortex development measurement. This paper aims to address this problem by presenting a method to reconstruct consistent cortical surfaces from longitudinal brain MR images in the first-year infants for accurate and consistent measurement of dynamic cortex development. Specifically, longitudinal development of the inner cortical surface is first modeled by a deformable sheet with elasto-plasticity property to establish longitudinally smooth correspondences of inner cortical surfaces. Then, the modeled longitudinal inner cortical surfaces are jointly deformed to locate inner and outer cortical surfaces with a spatial-temporal deformable surface. The method has been applied on 10 infants, each with 5 or 6 scans acquired at every 3 months from birth. Experimental results show that our method can accurately and consistently reconstruct dynamic cortical surfaces from longitudinal infant images, with the average surface distance as low as 0.2mm. By using our method, we can quantitatively characterize longitudinally dynamic cortical thickness development in the first-year infants.

KW - infant cortical thickness development

KW - infant longitudinal cortical surfaces

UR - http://www.scopus.com/inward/record.url?scp=84881631340&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84881631340&partnerID=8YFLogxK

U2 - 10.1109/ISBI.2013.6556790

DO - 10.1109/ISBI.2013.6556790

M3 - Conference contribution

AN - SCOPUS:84881631340

SN - 9781467364546

SP - 1380

EP - 1383

BT - Proceedings - International Symposium on Biomedical Imaging

ER -