Mechanical stress induced astaxanthin production on a chip

Junyi Yao, Sangil Han, Hyun Soo Kim, Younghak Cho, Yoon E. Choi, Jaewon Park

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Astaxanthin has been extensively studied in recent years due to its various pharmacological activities and high antioxidant capacity. Haematococcus pluvialis (H. pluvialis) is a type of microalgae that is capable of producing astaxanthin and it is also known to have the highest astaxanthin content in the nature. Here, we present a microfluidic culture platform that can culture flagellated stage of H. pluvialis under controlled mechanical stress for investigating its effect. The developed platform selectively cultured motile stage cells and approximately 15 times more astaxanthin accumulation was found with proper external mechanical stress applied during the 7 days of culture.

Original languageEnglish
Title of host publication22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018
PublisherChemical and Biological Microsystems Society
Pages1480-1481
Number of pages2
ISBN (Electronic)9781510897571
Publication statusPublished - 2018 Jan 1
Event22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018 - Kaohsiung, Taiwan, Province of China
Duration: 2018 Nov 112018 Nov 15

Publication series

Name22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018
Volume3

Conference

Conference22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018
CountryTaiwan, Province of China
CityKaohsiung
Period18/11/1118/11/15

Keywords

  • Astaxanthin
  • Haematococcus pluvialis
  • Mechanical stress
  • Microalgae

ASJC Scopus subject areas

  • Chemistry(all)
  • Bioengineering
  • Chemical Engineering (miscellaneous)
  • Control and Systems Engineering

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