Mercury ion-DNA specificity triggers a distinctive photoluminescence depression in organic semiconductor probes guided with a thymine-rich oligonucleotide sequence

Jietao Huang, Jin Hyuk Park, Seung Hyuk Back, Yuhui Feng, Chunzhi Cui, Long Yi Jin, Dong June Ahn

Research output: Contribution to journalArticle

Abstract

DNA strands have been recently found to play a role in crystallizing organic semiconductors as a substitute for conventional surfactants. Such DNA-guided organic semiconductor particles possessed the recognition ability to complementary target DNAs, resulting in "enhanced luminescence" due to the lesser degree of non-radiative dissipation. Apart from this, in this study we developed selective recognition of mercury ions by utilizing DNA probes having ion-specific thymine-rich motifs. Strikingly, the specific ion-DNA interaction triggered rather distinctive "depressed luminescence" emitting from the particles. The mercury ions were found to be present both at the surface and the inner regions, which were discovered to relate to the drastic morphological distortion of the particles as evidenced by elemental, electron microscopy, and confocal fluorescence microscopy analyses. This novel phenomenon discovered would expand the technological values of organic semiconductors conjugated with oligonucleotides toward a wider range of target-specific applications.

Original languageEnglish
Pages (from-to)17540-17545
Number of pages6
JournalNanoscale
Volume10
Issue number37
DOIs
Publication statusPublished - 2018 Oct 7

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Semiconducting organic compounds
Thymine
Oligonucleotides
Mercury
Photoluminescence
DNA
Ions
Luminescence
Confocal microscopy
Fluorescence microscopy
DNA Probes
Surface-Active Agents
Electron microscopy
Surface active agents

ASJC Scopus subject areas

  • Materials Science(all)

Cite this

Mercury ion-DNA specificity triggers a distinctive photoluminescence depression in organic semiconductor probes guided with a thymine-rich oligonucleotide sequence. / Huang, Jietao; Park, Jin Hyuk; Back, Seung Hyuk; Feng, Yuhui; Cui, Chunzhi; Jin, Long Yi; Ahn, Dong June.

In: Nanoscale, Vol. 10, No. 37, 07.10.2018, p. 17540-17545.

Research output: Contribution to journalArticle

Huang, Jietao ; Park, Jin Hyuk ; Back, Seung Hyuk ; Feng, Yuhui ; Cui, Chunzhi ; Jin, Long Yi ; Ahn, Dong June. / Mercury ion-DNA specificity triggers a distinctive photoluminescence depression in organic semiconductor probes guided with a thymine-rich oligonucleotide sequence. In: Nanoscale. 2018 ; Vol. 10, No. 37. pp. 17540-17545.
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