Metabolic engineering of solventogenic clostridia for butanol production

Sang Hyun Lee, Kyoung Heon Kim

Research output: Chapter in Book/Report/Conference proceedingChapter


Butanol can be produced by fermentation using solventogenic clostridia. However, economical production of butanol is hampered due to low fermentation efficiency and high substrate costs. To overcome these problems, genetic manipulations have been widely applied to solventogenic clostridia on the basis of systems metabolic engineering. This review mainly discusses the recent advances in strain development and improvements in fermentation performance.

Original languageEnglish
Title of host publicationEmerging Areas in Bioengineering
Number of pages18
ISBN (Electronic)9783527803286
ISBN (Print)9783527340880
Publication statusPublished - 2017 Jan 1


  • Butanol
  • Fermentation
  • Metabolic engineering
  • Solventogenic clostridia

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)


Dive into the research topics of 'Metabolic engineering of solventogenic clostridia for butanol production'. Together they form a unique fingerprint.

Cite this