Metal-free aerobic oxidative esterification of aldehydes in the presence of cyanide

Yoo Jin Kim, Cheol-Hong Cheon

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

A metal-free aerobic oxidative esterification of aldehydes in the presence of cyanide is described. Various aromatic aldehydes and sterically congested alcohols were amenable to this protocol. In addition, this method could be extended to the preparation of thioesters with a thiol in place of an alcohol. Furthermore, the cyanide-mediated aerobic oxidation of aldehydes was applied to the synthesis of lactones via intramolecular esterification in the absence of an alcohol.

Original languageEnglish
Pages (from-to)2055-2061
Number of pages7
JournalBulletin of the Korean Chemical Society
Volume36
Issue number8
DOIs
Publication statusPublished - 2015 Aug 1

Keywords

  • Aerobic oxidative esterification
  • Aldehydes
  • Cyanide
  • Oxidative lactonization
  • Thioester

ASJC Scopus subject areas

  • Chemistry(all)

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