Microencapsulation of insulin microcrystals

Sung Hee Choi, Jai Hyun Kwon, Chan Wha Kim

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

Insulin microcrystals were encapsulated (microcrystal/PLGA) within poly(lactide-co-glycolide) (PLGA 50:50) by the multiple emulsification solvent evaporation technique and compared with insulin solution microspheres (solution/PLGA) in terms of their morphology, size distribution, drug content, encapsulation efficiency, and stability of insulin during release.

Original languageEnglish
Pages (from-to)749-752
Number of pages4
JournalBioscience, Biotechnology and Biochemistry
Volume68
Issue number3
DOIs
Publication statusPublished - 2004 Mar 1

Fingerprint

Microencapsulation
microencapsulation
Drug Compounding
Microcrystals
insulin
Insulin
Polyglactin 910
Emulsification
emulsifying
encapsulation
Microspheres
Encapsulation
evaporation
Evaporation
drugs
Pharmaceutical Preparations
polylactic acid-polyglycolic acid copolymer
methodology

Keywords

  • Insulin
  • Microcrystal
  • Microsphere
  • Poly (lactide-co-glycolide) (PLGA)
  • Stability

ASJC Scopus subject areas

  • Food Science
  • Applied Microbiology and Biotechnology
  • Chemistry (miscellaneous)
  • Biochemistry, Genetics and Molecular Biology(all)
  • Biochemistry
  • Biotechnology

Cite this

Microencapsulation of insulin microcrystals. / Choi, Sung Hee; Kwon, Jai Hyun; Kim, Chan Wha.

In: Bioscience, Biotechnology and Biochemistry, Vol. 68, No. 3, 01.03.2004, p. 749-752.

Research output: Contribution to journalArticle

Choi, Sung Hee ; Kwon, Jai Hyun ; Kim, Chan Wha. / Microencapsulation of insulin microcrystals. In: Bioscience, Biotechnology and Biochemistry. 2004 ; Vol. 68, No. 3. pp. 749-752.
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