TY - GEN
T1 - Microfludics spinning of flat fiber with micro grooves for cell-aligning scaffolds
AU - Kang, Edward
AU - Choi, Yoon Young
AU - Choi, Yoon Jung
AU - Lee, Sang Hoon
N1 - Copyright:
Copyright 2014 Elsevier B.V., All rights reserved.
PY - 2012
Y1 - 2012
N2 - In this study, we propose a method for continuously fabricating alginate flat microfibers with size tunable grooved microstructures using a microfluidic system. By introducing a sheath fluid with a high-speed flow rate, an alginate solution could be both flattened and polymerized simultaneously. Raised patterns could be engraved on the surfaces of the flat fibers in the longitudinal direction, with successful control over the number and dimensions of microscale-grooves via regulation of the slit-shaped channel.
AB - In this study, we propose a method for continuously fabricating alginate flat microfibers with size tunable grooved microstructures using a microfluidic system. By introducing a sheath fluid with a high-speed flow rate, an alginate solution could be both flattened and polymerized simultaneously. Raised patterns could be engraved on the surfaces of the flat fibers in the longitudinal direction, with successful control over the number and dimensions of microscale-grooves via regulation of the slit-shaped channel.
KW - Cell alignment on patterned hydrogel
KW - Grooved flat fiber
KW - Microfluidic spinning
UR - http://www.scopus.com/inward/record.url?scp=84901747912&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84901747912&partnerID=8YFLogxK
M3 - Conference contribution
AN - SCOPUS:84901747912
SN - 9780979806452
T3 - Proceedings of the 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012
SP - 1726
EP - 1728
BT - Proceedings of the 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012
PB - Chemical and Biological Microsystems Society
T2 - 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012
Y2 - 28 October 2012 through 1 November 2012
ER -