Microfluidic chip-type electrochemical immunoassay for hippuric acid

Sung Ju Yoo, Young Bong Choi, Jongil Ju, Gun Sik Tae, Hyug Han Kim, Sang Hoon Lee

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

We describe a simple method for rapid and quantitative detection of hippuric acid (HA) by using PDMS-based microfluidic electrochemical immunosensor. The system employs a conjugate of ferrocene (Fc) and HA for the electrochemical detection. The competition between HA and the ferrocene-hippuric acid complex (Fc-Lys-HA) for HA antibody coated onto microbeads generates electrical signals proportional to HA concentration in the range of 0-40 mg/mL.

Original languageEnglish
Title of host publicationProceedings of Conference, MicroTAS 2009 - The 13th International Conference on Miniaturized Systems for Chemistry and Life Sciences
PublisherChemical and Biological Microsystems Society
Pages308-310
Number of pages3
ISBN (Print)9780979806421
Publication statusPublished - 2009
Event13th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2009 - Jeju, Korea, Republic of
Duration: 2009 Nov 12009 Nov 5

Publication series

NameProceedings of Conference, MicroTAS 2009 - The 13th International Conference on Miniaturized Systems for Chemistry and Life Sciences

Other

Other13th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2009
CountryKorea, Republic of
CityJeju
Period09/11/109/11/5

Keywords

  • Electrochemical immunosensor
  • Hippuric acid
  • Microfluidic chip
  • Small antigen

ASJC Scopus subject areas

  • Chemical Engineering (miscellaneous)
  • Bioengineering

Fingerprint Dive into the research topics of 'Microfluidic chip-type electrochemical immunoassay for hippuric acid'. Together they form a unique fingerprint.

  • Cite this

    Yoo, S. J., Choi, Y. B., Ju, J., Tae, G. S., Kim, H. H., & Lee, S. H. (2009). Microfluidic chip-type electrochemical immunoassay for hippuric acid. In Proceedings of Conference, MicroTAS 2009 - The 13th International Conference on Miniaturized Systems for Chemistry and Life Sciences (pp. 308-310). (Proceedings of Conference, MicroTAS 2009 - The 13th International Conference on Miniaturized Systems for Chemistry and Life Sciences). Chemical and Biological Microsystems Society.