Microfluidic chip-type electrochemical immunoassay for hippuric acid

Sung Ju Yoo, Young Bong Choi, Jongil Ju, Gun Sik Tae, Hyug Han Kim, Sang Hoon Lee

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

We describe a simple method for rapid and quantitative detection of hippuric acid (HA) by using PDMS-based microfluidic electrochemical immunosensor. The system employs a conjugate of ferrocene (Fc) and HA for the electrochemical detection. The competition between HA and the ferrocene-hippuric acid complex (Fc-Lys-HA) for HA antibody coated onto microbeads generates electrical signals proportional to HA concentration in the range of 0-40 mg/mL.

Original languageEnglish
Title of host publicationProceedings of Conference, MicroTAS 2009 - The 13th International Conference on Miniaturized Systems for Chemistry and Life Sciences
PublisherChemical and Biological Microsystems Society
Pages308-310
Number of pages3
ISBN (Print)9780979806421
Publication statusPublished - 2009 Jan 1
Event13th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2009 - Jeju, Korea, Republic of
Duration: 2009 Nov 12009 Nov 5

Other

Other13th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2009
CountryKorea, Republic of
CityJeju
Period09/11/109/11/5

Fingerprint

Microfluidics
Acids
Immunosensors
hippuric acid
Antibodies
ferrocene

ASJC Scopus subject areas

  • Chemical Engineering (miscellaneous)
  • Bioengineering

Cite this

Yoo, S. J., Choi, Y. B., Ju, J., Tae, G. S., Kim, H. H., & Lee, S. H. (2009). Microfluidic chip-type electrochemical immunoassay for hippuric acid. In Proceedings of Conference, MicroTAS 2009 - The 13th International Conference on Miniaturized Systems for Chemistry and Life Sciences (pp. 308-310). Chemical and Biological Microsystems Society.

Microfluidic chip-type electrochemical immunoassay for hippuric acid. / Yoo, Sung Ju; Choi, Young Bong; Ju, Jongil; Tae, Gun Sik; Kim, Hyug Han; Lee, Sang Hoon.

Proceedings of Conference, MicroTAS 2009 - The 13th International Conference on Miniaturized Systems for Chemistry and Life Sciences. Chemical and Biological Microsystems Society, 2009. p. 308-310.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Yoo, SJ, Choi, YB, Ju, J, Tae, GS, Kim, HH & Lee, SH 2009, Microfluidic chip-type electrochemical immunoassay for hippuric acid. in Proceedings of Conference, MicroTAS 2009 - The 13th International Conference on Miniaturized Systems for Chemistry and Life Sciences. Chemical and Biological Microsystems Society, pp. 308-310, 13th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2009, Jeju, Korea, Republic of, 09/11/1.
Yoo SJ, Choi YB, Ju J, Tae GS, Kim HH, Lee SH. Microfluidic chip-type electrochemical immunoassay for hippuric acid. In Proceedings of Conference, MicroTAS 2009 - The 13th International Conference on Miniaturized Systems for Chemistry and Life Sciences. Chemical and Biological Microsystems Society. 2009. p. 308-310
Yoo, Sung Ju ; Choi, Young Bong ; Ju, Jongil ; Tae, Gun Sik ; Kim, Hyug Han ; Lee, Sang Hoon. / Microfluidic chip-type electrochemical immunoassay for hippuric acid. Proceedings of Conference, MicroTAS 2009 - The 13th International Conference on Miniaturized Systems for Chemistry and Life Sciences. Chemical and Biological Microsystems Society, 2009. pp. 308-310
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