Microfluidic fabrication of microengineered hydrogels and their application in tissue engineering

Bong Geun Chung, Kwang Ho Lee, Ali Khademhosseini, Sang Hoon Lee

Research output: Contribution to journalReview articlepeer-review

267 Citations (Scopus)

Abstract

Microfluidic technologies are emerging as an enabling tool for various applications in tissue engineering and cell biology. One emerging use of microfluidic systems is the generation of shape-controlled hydrogels (i.e., microfibers, microparticles, and hydrogel building blocks) for various biological applications. Furthermore, the microfluidic fabrication of cell-laden hydrogels is of great benefit for creating artificial scaffolds. In this paper, we review the current development of microfluidic-based fabrication techniques for the creation of fibers, particles, and cell-laden hydrogels. We also highlight their emerging applications in tissue engineering and regenerative medicine.

Original languageEnglish
Pages (from-to)45-59
Number of pages15
JournalLab on a Chip
Volume12
Issue number1
DOIs
Publication statusPublished - 2012 Jan 7

ASJC Scopus subject areas

  • Bioengineering
  • Biochemistry
  • Chemistry(all)
  • Biomedical Engineering

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