Abstract
This paper reports microfluidic chip based wet spinning of biodegradable polymers with simple mechanism, and study of cell orientation dependence with fiber size. Biodegradable polymer PLGA fiber was produced by microfluidic chip based spinning device. By controlling feed rate of core polymer and sheath coagulating solutions, we got various PLGA fiber diameter from 10 to 242 μm. L929 mouse fibroblast cells were cultured on the surface of the fibers and the result showed unique tendency of cell orientation on the fibers.
| Original language | English |
|---|---|
| Title of host publication | 12th International Conference on Miniaturized Systems for Chemistry and Life Sciences - The Proceedings of MicroTAS 2008 Conference |
| Publisher | Chemical and Biological Microsystems Society |
| Pages | 131-133 |
| Number of pages | 3 |
| Publication status | Published - 2008 Jan 1 |
| Event | 12th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2008 - San Diego, CA, United States Duration: 2008 Oct 12 → 2008 Oct 16 |
Other
| Other | 12th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2008 |
|---|---|
| Country | United States |
| City | San Diego, CA |
| Period | 08/10/12 → 08/10/16 |
ASJC Scopus subject areas
- Chemical Engineering (miscellaneous)
- Bioengineering
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Cite this
Hwang, C. M., Sun, K., Khademhosseini, A., & Lee, S. H. (2008). Microfluidic spinning of biodegradable polymer and cell orientation control on the fibers. In 12th International Conference on Miniaturized Systems for Chemistry and Life Sciences - The Proceedings of MicroTAS 2008 Conference (pp. 131-133). Chemical and Biological Microsystems Society.