Microfluidic spinning of flat alginate fibers with grooves for cell-aligning scaffolds

Edward Kang, Yoon Young Choi, Su Kyoung Chae, Jin Hee Moon, Joon Young Chang, Sang Hoon Lee

Research output: Contribution to journalArticle

117 Citations (Scopus)

Abstract

Alginate microribbons with longitudinally grooved microstructures are continuously fabricated by means of a microfluidic system. The number and dimensions of the microgroovesare successfully controlled by regulation of the slit-shaped channel (yellow in figure). This method opens up the possibility of mass production of scaffolds for tissue engineering purposes, as it is proved that the grooved flat fibers can be used to align other types of cells in culture.

Original languageEnglish
Pages (from-to)4271-4277
Number of pages7
JournalAdvanced Materials
Volume24
Issue number31
DOIs
Publication statusPublished - 2012 Aug 16

Fingerprint

Alginate
Scaffolds (biology)
Tissue engineering
Microfluidics
Scaffolds
Microstructure
Fibers
alginic acid

Keywords

  • alginates
  • cell alignment
  • fibers
  • grooved
  • microfluidic spinning
  • microstructures
  • patterned
  • ribbons

ASJC Scopus subject areas

  • Materials Science(all)
  • Mechanics of Materials
  • Mechanical Engineering

Cite this

Microfluidic spinning of flat alginate fibers with grooves for cell-aligning scaffolds. / Kang, Edward; Choi, Yoon Young; Chae, Su Kyoung; Moon, Jin Hee; Chang, Joon Young; Lee, Sang Hoon.

In: Advanced Materials, Vol. 24, No. 31, 16.08.2012, p. 4271-4277.

Research output: Contribution to journalArticle

Kang, Edward ; Choi, Yoon Young ; Chae, Su Kyoung ; Moon, Jin Hee ; Chang, Joon Young ; Lee, Sang Hoon. / Microfluidic spinning of flat alginate fibers with grooves for cell-aligning scaffolds. In: Advanced Materials. 2012 ; Vol. 24, No. 31. pp. 4271-4277.
@article{38ab55277daa47ecbf49575998ddc60d,
title = "Microfluidic spinning of flat alginate fibers with grooves for cell-aligning scaffolds",
abstract = "Alginate microribbons with longitudinally grooved microstructures are continuously fabricated by means of a microfluidic system. The number and dimensions of the microgroovesare successfully controlled by regulation of the slit-shaped channel (yellow in figure). This method opens up the possibility of mass production of scaffolds for tissue engineering purposes, as it is proved that the grooved flat fibers can be used to align other types of cells in culture.",
keywords = "alginates, cell alignment, fibers, grooved, microfluidic spinning, microstructures, patterned, ribbons",
author = "Edward Kang and Choi, {Yoon Young} and Chae, {Su Kyoung} and Moon, {Jin Hee} and Chang, {Joon Young} and Lee, {Sang Hoon}",
year = "2012",
month = "8",
day = "16",
doi = "10.1002/adma.201201232",
language = "English",
volume = "24",
pages = "4271--4277",
journal = "Advanced Materials",
issn = "0935-9648",
publisher = "Wiley-VCH Verlag",
number = "31",

}

TY - JOUR

T1 - Microfluidic spinning of flat alginate fibers with grooves for cell-aligning scaffolds

AU - Kang, Edward

AU - Choi, Yoon Young

AU - Chae, Su Kyoung

AU - Moon, Jin Hee

AU - Chang, Joon Young

AU - Lee, Sang Hoon

PY - 2012/8/16

Y1 - 2012/8/16

N2 - Alginate microribbons with longitudinally grooved microstructures are continuously fabricated by means of a microfluidic system. The number and dimensions of the microgroovesare successfully controlled by regulation of the slit-shaped channel (yellow in figure). This method opens up the possibility of mass production of scaffolds for tissue engineering purposes, as it is proved that the grooved flat fibers can be used to align other types of cells in culture.

AB - Alginate microribbons with longitudinally grooved microstructures are continuously fabricated by means of a microfluidic system. The number and dimensions of the microgroovesare successfully controlled by regulation of the slit-shaped channel (yellow in figure). This method opens up the possibility of mass production of scaffolds for tissue engineering purposes, as it is proved that the grooved flat fibers can be used to align other types of cells in culture.

KW - alginates

KW - cell alignment

KW - fibers

KW - grooved

KW - microfluidic spinning

KW - microstructures

KW - patterned

KW - ribbons

UR - http://www.scopus.com/inward/record.url?scp=84864678930&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84864678930&partnerID=8YFLogxK

U2 - 10.1002/adma.201201232

DO - 10.1002/adma.201201232

M3 - Article

C2 - 22740066

AN - SCOPUS:84864678930

VL - 24

SP - 4271

EP - 4277

JO - Advanced Materials

JF - Advanced Materials

SN - 0935-9648

IS - 31

ER -