Microfluidic spinning of micro- and nano-scale fibers for tissue engineering

Yesl Jun, Edward Kang, Sukyoung Chae, Sang Hoon Lee

Research output: Contribution to journalArticle

174 Citations (Scopus)

Abstract

Microfluidic technologies have recently been shown to hold significant potential as novel tools for producing micro- and nano-scale structures for a variety of applications in tissue engineering and cell biology. Over the last decade, microfluidic spinning has emerged as an advanced method for fabricating fibers with diverse shapes and sizes without the use of complicated devices or facilities. In this critical review, we describe the current development of microfluidic-based spinning techniques for producing micro- and nano-scale fibers based on different solidification methods, platforms, geometries, or biomaterials. We also highlight the emerging applications of fibers as bottom-up scaffolds such as cell encapsulation or guidance for use in tissue engineering research and clinical practice.

Original languageEnglish
Pages (from-to)2145-2160
Number of pages16
JournalLab on a Chip - Miniaturisation for Chemistry and Biology
Volume14
Issue number13
DOIs
Publication statusPublished - 2014 Jul 7

ASJC Scopus subject areas

  • Biochemistry
  • Chemistry(all)
  • Bioengineering
  • Biomedical Engineering

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