Microfluidic valve employing the pH-responsive hydrogel microsphere as an actuating element

Ji Young Park, Duck Joong Kim, Sung Rak Kim, Ju Yeoul Baek, Kyung Sun, Sang Hoon Lee

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

In this paper, we propose a new fabrication method of pH-responsive microfluidic Valves and suggest the feasibility as a microminiature systems without peripheral devices. Conventionally, in-situ photopolymerization method has been employed to build the micro functional structure inside microfluidic channel. Here, we suggest a new method allowing the mass production of stimuli-responsive microsystem through the use of pre-made microstructure as actuating element like assembly of commercial products in the factory. We have massively fabricated pH-responsive microspheres, that act as actuating component through the use of PDMS-based microfluidic apparatus and 'on the fly' photopolymerization method. By the incorporation of this microsphere into the microvalve during the fabrication process, we have produced the pH-responsive microfluidic valve in a simple way. The operation and the function of the fabricated microvalve were evaluated through the diverse experiments. The microvalve was successfully fabricated, and functioned well according to the pH change.

Original languageEnglish
Title of host publicationProceedings of 2006 International Conference on Microtechnologies in Medicine and Biology
Pages35-38
Number of pages4
DOIs
Publication statusPublished - 2006 Dec 1
Event2006 International Conference on Microtechnologies in Medicine and Biology - Okinawa, Japan
Duration: 2006 May 92006 May 12

Other

Other2006 International Conference on Microtechnologies in Medicine and Biology
CountryJapan
CityOkinawa
Period06/5/906/5/12

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Keywords

  • Microfluidic
  • Microsphere
  • Microvalve
  • pH-responsive

ASJC Scopus subject areas

  • Biomedical Engineering
  • Electrical and Electronic Engineering
  • Medicine(all)

Cite this

Park, J. Y., Kim, D. J., Kim, S. R., Baek, J. Y., Sun, K., & Lee, S. H. (2006). Microfluidic valve employing the pH-responsive hydrogel microsphere as an actuating element. In Proceedings of 2006 International Conference on Microtechnologies in Medicine and Biology (pp. 35-38). [4281301] https://doi.org/10.1109/MMB.2006.251483