Microvascular integrity as a predictor of left ventricular remodeling after acute anterior wall myocardial infarction

Wan Joo Shim, Eun Mi Lee, Gyo Seung Hwang, Jeong Cheon Ahn, Woohyuk Song, Do-Sun Lim, Chang Gyu Park, Young Hoon Kim, Mong Seog Seo, Dong Joo Oh, Young Moo Ro

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

The purpose of this study was to investigate the relation of microvascular integrity and ventricular remodeling after acute myocardial infarction. Twenty-six patients with first acute anterior myocardial infarction were studied before discharge with myocardial contrast echocardiography (MCE). Opacification index (OI) and wall motion index were calculated in the left anterior descending artery territory and left ventricular diastolic volume was measured at baseline and during a 9-month follow-up. In total 26 patients, the regional wall motion improved but the left ventricular volume and global function was not changed significantly at follow-up. When the patients were divided into 3 groups according to opacification index (≥0.75, 0.5-0.75, ≤0.5) at baseline, functional recovery was not observed and significant left ventricular dilatation was developed in patients with ≤0.5 OI. Among the baseline echo-parameters such as ejection fraction, wall motion score, left ventricular volume and opacification index, the best predictor for long term left ventricular dilatation was the opacification index by multivariate analysis. In patients with acute anterior wall infarction the assessment of microvascular integrity by MCE at acute stage provides useful information regarding recovery of dysfunctional regional wall motion and ventricular remodeling.

Original languageEnglish
Pages (from-to)466-472
Number of pages7
JournalJournal of Korean Medical Science
Volume13
Issue number5
Publication statusPublished - 1998 Oct 1

Fingerprint

Anterior Wall Myocardial Infarction
Ventricular Remodeling
Echocardiography
Dilatation
Myocardial Infarction
Infarction
Multivariate Analysis
Arteries

Keywords

  • Echocardiography
  • Myocardial diseases
  • Myocardial infarction
  • Ventricular remodeling

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Microvascular integrity as a predictor of left ventricular remodeling after acute anterior wall myocardial infarction. / Shim, Wan Joo; Lee, Eun Mi; Hwang, Gyo Seung; Ahn, Jeong Cheon; Song, Woohyuk; Lim, Do-Sun; Park, Chang Gyu; Kim, Young Hoon; Seo, Mong Seog; Oh, Dong Joo; Ro, Young Moo.

In: Journal of Korean Medical Science, Vol. 13, No. 5, 01.10.1998, p. 466-472.

Research output: Contribution to journalArticle

Shim, Wan Joo ; Lee, Eun Mi ; Hwang, Gyo Seung ; Ahn, Jeong Cheon ; Song, Woohyuk ; Lim, Do-Sun ; Park, Chang Gyu ; Kim, Young Hoon ; Seo, Mong Seog ; Oh, Dong Joo ; Ro, Young Moo. / Microvascular integrity as a predictor of left ventricular remodeling after acute anterior wall myocardial infarction. In: Journal of Korean Medical Science. 1998 ; Vol. 13, No. 5. pp. 466-472.
@article{6e40385d1e05497589706a8dabd09314,
title = "Microvascular integrity as a predictor of left ventricular remodeling after acute anterior wall myocardial infarction",
abstract = "The purpose of this study was to investigate the relation of microvascular integrity and ventricular remodeling after acute myocardial infarction. Twenty-six patients with first acute anterior myocardial infarction were studied before discharge with myocardial contrast echocardiography (MCE). Opacification index (OI) and wall motion index were calculated in the left anterior descending artery territory and left ventricular diastolic volume was measured at baseline and during a 9-month follow-up. In total 26 patients, the regional wall motion improved but the left ventricular volume and global function was not changed significantly at follow-up. When the patients were divided into 3 groups according to opacification index (≥0.75, 0.5-0.75, ≤0.5) at baseline, functional recovery was not observed and significant left ventricular dilatation was developed in patients with ≤0.5 OI. Among the baseline echo-parameters such as ejection fraction, wall motion score, left ventricular volume and opacification index, the best predictor for long term left ventricular dilatation was the opacification index by multivariate analysis. In patients with acute anterior wall infarction the assessment of microvascular integrity by MCE at acute stage provides useful information regarding recovery of dysfunctional regional wall motion and ventricular remodeling.",
keywords = "Echocardiography, Myocardial diseases, Myocardial infarction, Ventricular remodeling",
author = "Shim, {Wan Joo} and Lee, {Eun Mi} and Hwang, {Gyo Seung} and Ahn, {Jeong Cheon} and Woohyuk Song and Do-Sun Lim and Park, {Chang Gyu} and Kim, {Young Hoon} and Seo, {Mong Seog} and Oh, {Dong Joo} and Ro, {Young Moo}",
year = "1998",
month = "10",
day = "1",
language = "English",
volume = "13",
pages = "466--472",
journal = "Journal of Korean Medical Science",
issn = "1011-8934",
publisher = "Korean Academy of Medical Science",
number = "5",

}

TY - JOUR

T1 - Microvascular integrity as a predictor of left ventricular remodeling after acute anterior wall myocardial infarction

AU - Shim, Wan Joo

AU - Lee, Eun Mi

AU - Hwang, Gyo Seung

AU - Ahn, Jeong Cheon

AU - Song, Woohyuk

AU - Lim, Do-Sun

AU - Park, Chang Gyu

AU - Kim, Young Hoon

AU - Seo, Mong Seog

AU - Oh, Dong Joo

AU - Ro, Young Moo

PY - 1998/10/1

Y1 - 1998/10/1

N2 - The purpose of this study was to investigate the relation of microvascular integrity and ventricular remodeling after acute myocardial infarction. Twenty-six patients with first acute anterior myocardial infarction were studied before discharge with myocardial contrast echocardiography (MCE). Opacification index (OI) and wall motion index were calculated in the left anterior descending artery territory and left ventricular diastolic volume was measured at baseline and during a 9-month follow-up. In total 26 patients, the regional wall motion improved but the left ventricular volume and global function was not changed significantly at follow-up. When the patients were divided into 3 groups according to opacification index (≥0.75, 0.5-0.75, ≤0.5) at baseline, functional recovery was not observed and significant left ventricular dilatation was developed in patients with ≤0.5 OI. Among the baseline echo-parameters such as ejection fraction, wall motion score, left ventricular volume and opacification index, the best predictor for long term left ventricular dilatation was the opacification index by multivariate analysis. In patients with acute anterior wall infarction the assessment of microvascular integrity by MCE at acute stage provides useful information regarding recovery of dysfunctional regional wall motion and ventricular remodeling.

AB - The purpose of this study was to investigate the relation of microvascular integrity and ventricular remodeling after acute myocardial infarction. Twenty-six patients with first acute anterior myocardial infarction were studied before discharge with myocardial contrast echocardiography (MCE). Opacification index (OI) and wall motion index were calculated in the left anterior descending artery territory and left ventricular diastolic volume was measured at baseline and during a 9-month follow-up. In total 26 patients, the regional wall motion improved but the left ventricular volume and global function was not changed significantly at follow-up. When the patients were divided into 3 groups according to opacification index (≥0.75, 0.5-0.75, ≤0.5) at baseline, functional recovery was not observed and significant left ventricular dilatation was developed in patients with ≤0.5 OI. Among the baseline echo-parameters such as ejection fraction, wall motion score, left ventricular volume and opacification index, the best predictor for long term left ventricular dilatation was the opacification index by multivariate analysis. In patients with acute anterior wall infarction the assessment of microvascular integrity by MCE at acute stage provides useful information regarding recovery of dysfunctional regional wall motion and ventricular remodeling.

KW - Echocardiography

KW - Myocardial diseases

KW - Myocardial infarction

KW - Ventricular remodeling

UR - http://www.scopus.com/inward/record.url?scp=0032177452&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0032177452&partnerID=8YFLogxK

M3 - Article

VL - 13

SP - 466

EP - 472

JO - Journal of Korean Medical Science

JF - Journal of Korean Medical Science

SN - 1011-8934

IS - 5

ER -