Microwave-assisted amination of 3-bromo-2-chloropyridine with various substituted aminoethanols

Jeong Geun Kim, Eun Hae Yang, Woo Sup Youn, Ji Won Choi, Deok-Chan Ha, Jae Du Ha

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3 Citations (Scopus)

Abstract

A simple method for microwave-assisted amination of 3-bromo-2-chloropyridine with various substituted aminoethanols is described. The reaction was carried out under microwave irradiation conditions (at 180 °C for 1-2 h) and the result was superior in terms of conversion and yield when compared to that of the corresponding conventional heating conditions.

Original languageEnglish
Pages (from-to)3886-3889
Number of pages4
JournalTetrahedron Letters
Volume51
Issue number30
DOIs
Publication statusPublished - 2010 Jul 28

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Keywords

  • 3-Bromo-2-chloropyridine
  • Aminoethanol
  • Microwave-assisted amination
  • Pyrido[1,4]oxazine

ASJC Scopus subject areas

  • Biochemistry
  • Organic Chemistry
  • Drug Discovery

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