Modified complete mesocolic excision with central vascular ligation for the treatment of right-sided colon cancer: Long-term outcomes and prognostic factors

Min Soo Cho, Se-Jin Baek, Hyuk Hur, Byung Soh Min, Seung Hyuk Baik, Nam Kyu Kim

Research output: Contribution to journalArticle

40 Citations (Scopus)

Abstract

Objective: to Investigate the Long-term Oncologic Outcomes and Risk Factors for Adverse Effects in Rt.-sided Colon Cancer Patients Who Underwent Modified Complete Mesocolic Excision . Background: Complete Mesocolic Excision with Ctrl. Vasc. Ligation Has Recently Been Found to Improve Oncological Outcomes in Patients with Colon Cancer. Our Inst. Has Estab. MCME on the Basis of the Original Concept of CME for the Treatm. of Rt.-sided Colon Cancer. Methods: between January 2000 and July 2009, 773 Patients Who Underwent MCME for Rt.-sided Colon Cancer Were Eligible for This Retrospective Stud.. the Prognostic Factors for Survival/recurrence and the Risk Factors for Postoperative Complications Were Investigated. Results: the Mean Follow-up Period Was 61.9-34.7 Months. the 5-Yr. Overall Survival and 5-Yr. Dis.-free Survival Rates Were 84.0% and 82.8%, Respectively. Pathologic Stage III Dis., Postoperative Complications, Age More Than 60 Years, and Minimally Invasive Surg. Were Found to Be Ind. Prognostic Factors. the 5-Yr. Locoregional Recurrence and 5-Yr. Systemic Recurrence Rates Were 4.9% and 13.7%, Respectively. the Risk of LRR and SRR Increased with Pathologic Stage III Dis.. An Amer. Soc. of Anesth. Score of Higher Than II Was An Ind. Predictive Factor of Postoperative Complications. Conclusions: We Have Successfully Estab. the MCME Tech., on the Basis of the Same Principle As CME, but with A More Tailored Approach. the Long-termoncologic Outcomes and Risk of Postoperative Morbidity Were Found to Be Comparable with Those Seen with the Original CME Procedure.

Original languageEnglish
Pages (from-to)708-715
Number of pages8
JournalAnnals of surgery
Volume261
Issue number4
DOIs
Publication statusPublished - 2015 Apr 1
Externally publishedYes

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Colonic Neoplasms
Ligation
Blood Vessels
Recurrence
Survival
Therapeutics
Survival Rate
Morbidity

Keywords

  • Modified complete mesocolic excision
  • Oncologic outcomes
  • Prognostic factor
  • Right-sided colon cancer

ASJC Scopus subject areas

  • Surgery

Cite this

Modified complete mesocolic excision with central vascular ligation for the treatment of right-sided colon cancer : Long-term outcomes and prognostic factors. / Cho, Min Soo; Baek, Se-Jin; Hur, Hyuk; Min, Byung Soh; Baik, Seung Hyuk; Kim, Nam Kyu.

In: Annals of surgery, Vol. 261, No. 4, 01.04.2015, p. 708-715.

Research output: Contribution to journalArticle

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abstract = "Objective: to Investigate the Long-term Oncologic Outcomes and Risk Factors for Adverse Effects in Rt.-sided Colon Cancer Patients Who Underwent Modified Complete Mesocolic Excision . Background: Complete Mesocolic Excision with Ctrl. Vasc. Ligation Has Recently Been Found to Improve Oncological Outcomes in Patients with Colon Cancer. Our Inst. Has Estab. MCME on the Basis of the Original Concept of CME for the Treatm. of Rt.-sided Colon Cancer. Methods: between January 2000 and July 2009, 773 Patients Who Underwent MCME for Rt.-sided Colon Cancer Were Eligible for This Retrospective Stud.. the Prognostic Factors for Survival/recurrence and the Risk Factors for Postoperative Complications Were Investigated. Results: the Mean Follow-up Period Was 61.9-34.7 Months. the 5-Yr. Overall Survival and 5-Yr. Dis.-free Survival Rates Were 84.0{\%} and 82.8{\%}, Respectively. Pathologic Stage III Dis., Postoperative Complications, Age More Than 60 Years, and Minimally Invasive Surg. Were Found to Be Ind. Prognostic Factors. the 5-Yr. Locoregional Recurrence and 5-Yr. Systemic Recurrence Rates Were 4.9{\%} and 13.7{\%}, Respectively. the Risk of LRR and SRR Increased with Pathologic Stage III Dis.. An Amer. Soc. of Anesth. Score of Higher Than II Was An Ind. Predictive Factor of Postoperative Complications. Conclusions: We Have Successfully Estab. the MCME Tech., on the Basis of the Same Principle As CME, but with A More Tailored Approach. the Long-termoncologic Outcomes and Risk of Postoperative Morbidity Were Found to Be Comparable with Those Seen with the Original CME Procedure.",
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AU - Min, Byung Soh

AU - Baik, Seung Hyuk

AU - Kim, Nam Kyu

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